A case of intravascular papillary endothelial hyperplasia on the sole

Abstract

Intravascular papillary endothelial hyperplasia (IPEH), a benign, reactive vascular lesion, is characterized by the development of endothelial-lined papillary projections in a vascular lumen. Although there has been some controversy about the nature of IPEH, most investigators favor the idea that IPEH usually results from a peculiar organization of a thrombus. The lesions are frequently located in the subcutis of the fingers, hands, forearms, head and neck as a solitary, often tender, bluish or reddish nodule. We report a rare case of IPEH arising on the left sole, an unusual site. IPEH should be among the differential diagnosis of tender lesions on the soles.