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Chitosan and its derivatives for gene delivery

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dc.contributor.authorLee, Kuen Yong-
dc.date.accessioned2022-12-21T08:46:58Z-
dc.date.available2022-12-21T08:46:58Z-
dc.date.created2022-08-26-
dc.date.issued2007-04-
dc.identifier.issn1598-5032-
dc.identifier.urihttps://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/180261-
dc.description.abstractNon-viral vectors, including lipid- or polymer-based systems, have attracted much attention to date as a gene delivery vehicle, due to safety issues with viral vectors. Chitosan, a naturally existing cationic polymer, has shown great potential as a gene delivery carrier, as it has low immunogenicity and toxicity, excellent transcellular transport ability, and is relatively easy to chemically modify. This review summarizes and discusses the general features of chitosan and its applications as a delivery carrier of DNA and RNA.-
dc.language영어-
dc.language.isoen-
dc.publisherSPRINGER-
dc.titleChitosan and its derivatives for gene delivery-
dc.typeArticle-
dc.contributor.affiliatedAuthorLee, Kuen Yong-
dc.identifier.doi10.1007/BF03218774-
dc.identifier.scopusid2-s2.0-34248227817-
dc.identifier.wosid000246316400001-
dc.identifier.bibliographicCitationMACROMOLECULAR RESEARCH, v.15, no.3, pp.195 - 201-
dc.relation.isPartOfMACROMOLECULAR RESEARCH-
dc.citation.titleMACROMOLECULAR RESEARCH-
dc.citation.volume15-
dc.citation.number3-
dc.citation.startPage195-
dc.citation.endPage201-
dc.type.rimsART-
dc.type.docTypeReview-
dc.identifier.kciidART001052297-
dc.description.journalClass1-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.description.journalRegisteredClasskci-
dc.relation.journalResearchAreaPolymer Science-
dc.relation.journalWebOfScienceCategoryPolymer Science-
dc.subject.keywordPlusACID-MODIFIED CHITOSAN-
dc.subject.keywordPlusIN-VIVO-
dc.subject.keywordPlusPLASMID DNA-
dc.subject.keywordPlusTRANSFECTION EFFICIENCY-
dc.subject.keywordPlusMOLECULAR-WEIGHT-
dc.subject.keywordPlusBLOCK-COPOLYMERS-
dc.subject.keywordPlusNANOPARTICLES-
dc.subject.keywordPlusTHERAPY-
dc.subject.keywordPlusCOMPLEXES-
dc.subject.keywordPlusCHITIN-
dc.subject.keywordAuthorchitosan-
dc.subject.keywordAuthornanoparticle-
dc.subject.keywordAuthorgene delivery-
dc.subject.keywordAuthortargeting-
dc.subject.keywordAuthorsiRNA-
dc.identifier.urlhttps://link.springer.com/article/10.1007/BF03218774-
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