한국인 알코올 간염 환자의 예후 판정을 위한 Discriminant Function 점수, Child-Turcotte-Pugh 점수와 Model for End-stage Liver Disease 점수 비교
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 정재윤 | - |
dc.contributor.author | 손주현 | - |
dc.contributor.author | 손병관 | - |
dc.contributor.author | 백창희 | - |
dc.contributor.author | 김석환 | - |
dc.contributor.author | 한동수 | - |
dc.contributor.author | 전용철 | - |
dc.contributor.author | 이민호 | - |
dc.contributor.author | 이동후 | - |
dc.contributor.author | 기춘석 | - |
dc.date.accessioned | 2022-12-21T09:09:10Z | - |
dc.date.available | 2022-12-21T09:09:10Z | - |
dc.date.created | 2022-09-16 | - |
dc.date.issued | 2007-02 | - |
dc.identifier.issn | 1598-9992 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/180468 | - |
dc.description.abstract | BACKGROUND/AIMS: Alcoholic hepatitis is an acute or acute-on-chronic inflammatory syndrome associated with significant morbidity and mortality. Traditionally, Maddrey discriminant function (DF) score and Child-Turcott-Pugh (CTP) score have been used for stratifying the prognosis of alcoholic hepatitis. Recently, the model for end-stage liver disease (MELD) score has been applied to alcoholic hepatitis and some investigators consider MELD score as a better prognostic indicator for severe alcoholic hepatitis. Therefore, this analysis was aimed to compare MELD score with DF and CTP scores for predicting the short-term mortality in Korean patients with alcoholic hepatitis. METHODS: The medical records of patients hospitalized with alcoholic hepatitis between January 1, 1999 and December 31, 2004 at Hanyang University Guri-Hospital were analyzed retrospectively. RESULTS: Of the 138 medical records reviewed, 74 cases fulfilled the inclusion criteria (61 males and 13 females; mean age 47.1 years). Twelve patients (16.2%) died within 90 days after admission. Univariate analysis demonstrated that variables such as ascites, hepatic encephalopathy, splenomegaly, international normalized ratio, CTP, and DF scores were significantly correlated with increased 90-day mortality while MELD score was not. According to the multivariate analysis, only CTP score was statistically significant (p=0.012) while DF and MELD scores were not significant for predicting 90-day mortality. The survival analysis with Cox regression test showed higher DF and CTP scores, but not MELD score, significantly increased the risk of in-hospital mortality. CONCLUSIONS: This study demonstrates that DF and CTP scores are independent predictors of short-term mortality in patients with alcoholic hepatitis. | - |
dc.language | 한국어 | - |
dc.language.iso | ko | - |
dc.publisher | 대한소화기학회 | - |
dc.title | 한국인 알코올 간염 환자의 예후 판정을 위한 Discriminant Function 점수, Child-Turcotte-Pugh 점수와 Model for End-stage Liver Disease 점수 비교 | - |
dc.title.alternative | Comparison of model for end-stage liver disease score with discriminant function and child-Turcotte-Pugh scores for predicting short-term mortality in Korean patients with alcoholic hepatitis | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | 손주현 | - |
dc.contributor.affiliatedAuthor | 한동수 | - |
dc.contributor.affiliatedAuthor | 전용철 | - |
dc.identifier.scopusid | 2-s2.0-53749097062 | - |
dc.identifier.bibliographicCitation | The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, v.49, no.2, pp.93 - 99 | - |
dc.relation.isPartOf | The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi | - |
dc.citation.title | The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi | - |
dc.citation.volume | 49 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 93 | - |
dc.citation.endPage | 99 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001187939 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordPlus | adult | - |
dc.subject.keywordPlus | alcohol liver disease | - |
dc.subject.keywordPlus | article | - |
dc.subject.keywordPlus | comparative study | - |
dc.subject.keywordPlus | female | - |
dc.subject.keywordPlus | follow up | - |
dc.subject.keywordPlus | hospitalization | - |
dc.subject.keywordPlus | human | - |
dc.subject.keywordPlus | Korea | - |
dc.subject.keywordPlus | liver disease | - |
dc.subject.keywordPlus | male | - |
dc.subject.keywordPlus | middle aged | - |
dc.subject.keywordPlus | mortality | - |
dc.subject.keywordPlus | prediction and forecasting | - |
dc.subject.keywordPlus | prognosis | - |
dc.subject.keywordPlus | roc curve | - |
dc.subject.keywordPlus | survival | - |
dc.subject.keywordPlus | time | - |
dc.subject.keywordPlus | Adult | - |
dc.subject.keywordPlus | Female | - |
dc.subject.keywordPlus | Follow-Up Studies | - |
dc.subject.keywordPlus | Hepatitis, Alcoholic | - |
dc.subject.keywordPlus | Humans | - |
dc.subject.keywordPlus | Korea | - |
dc.subject.keywordPlus | Liver Diseases | - |
dc.subject.keywordPlus | Male | - |
dc.subject.keywordPlus | Middle Aged | - |
dc.subject.keywordPlus | Predictive Value of Tests | - |
dc.subject.keywordPlus | Prognosis | - |
dc.subject.keywordPlus | ROC Curve | - |
dc.subject.keywordPlus | Severity of Illness Index | - |
dc.subject.keywordPlus | Survival Analysis | - |
dc.subject.keywordPlus | Time Factors | - |
dc.subject.keywordAuthor | Alcoholic hepatitis | - |
dc.subject.keywordAuthor | Mortality | - |
dc.subject.keywordAuthor | Prognosis | - |
dc.identifier.url | https://www.kjg.or.kr/journal/view.html?uid=3756&vmd=Full | - |
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