혈청 음성 Celiac 병을 의심하는 소장 융모 위축과 연관된 단백상실장병증 1예A Case of Protein-losing Enteropathy Associated with Small Bowel Villous Atrophy
- Other Titles
- A Case of Protein-losing Enteropathy Associated with Small Bowel Villous Atrophy
- Authors
- 한성희; 이오영; 은창수; 노병주; 손원; 백승삼; 윤병철; 최호순
- Issue Date
- Jan-2007
- Publisher
- 대한소화기학회
- Keywords
- Protein losing enteropathy; Small bowel villous atrophy; Celiac disease; Protein losing enteropathy; Small bowel villous atrophy; Celiac disease
- Citation
- The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, v.49, no.1, pp.31 - 36
- Indexed
- SCOPUS
KCI
- Journal Title
- The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
- Volume
- 49
- Number
- 1
- Start Page
- 31
- End Page
- 36
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/180550
- ISSN
- 1598-9992
- Abstract
- Protein losing enteropathy is described as a diverse group of disorders associated with excessive loss of serum proteins into the gastrointestinal (GI) tract. The etiology of protein losing enteropathy is various. Increased mucosal permeability to protein as a result of cell damage, mucosal erosion, or lymphatic obstruction may develop protein losing enteropathy. Celiac disease is a common cause of protein losing enteropathy associated with small bowel villous atrophy in Europe. We experienced a case of protein losing enteropathy associated with small bowel villous atrophy of unknown origin. A 36-year-old woman was admitted due to chronic watery diarrhea and weight loss. Laboratory findings showed total protein 4.7 g/dL, albumin 2.7 g/dL, cholesterol 100 mg/dL, WBC 6,000/mm3 (lymphocyte 13.6%) with the absence of proteinuria. On esophagogastroduodenoscopic examination, duodenal ulcer scar was noted on the bulb and colonoscopic finding was nonspecific. On small bowel enteroscopy, jejunal and ileal villi was scantly noticed. Small bowel biopsy showed marked villous atrophy. Her symptoms did not improve after supportive care. Gluten free diet was tried because celiac disease could not be ruled out completely. Diarrhea ceased and body weight regained after gluten free diet.
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