Profiling of differentially expressed genes in human stem cells by cDNA microarray
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Chul Geun | - |
dc.contributor.author | Lee, Jong Joo | - |
dc.contributor.author | Jung, Dae Young | - |
dc.contributor.author | Jeon, Jinseon | - |
dc.contributor.author | Heo, Hyen Seok | - |
dc.contributor.author | Kang, Ho Chul | - |
dc.contributor.author | Shin, June Ho | - |
dc.contributor.author | Cho, Yoon Shin | - |
dc.contributor.author | Chat, Kyung Joon | - |
dc.contributor.author | Kim, Chan Gil | - |
dc.contributor.author | Do, Byung-Rok | - |
dc.contributor.author | Kim, Kyung Suk | - |
dc.contributor.author | Kims, Hyun-Soo | - |
dc.date.accessioned | 2022-12-21T11:12:57Z | - |
dc.date.available | 2022-12-21T11:12:57Z | - |
dc.date.created | 2022-09-16 | - |
dc.date.issued | 2006-06 | - |
dc.identifier.issn | 1016-8478 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/181400 | - |
dc.description.abstract | Stem cells are unique cell populations with the ability to undergo both self-renewal and differentiation, although a wide variety of adult stem cells as well as embryonic stem cells have been identified and stem cell plasticity has recently been reported. To identify genes implicated in the control of the stem cell state as well as the characteristics of each stem cell line, we analyzed the expression profiles of genes in human embryonic, hematopoietic (CD34(+) and CD133(+)), and mesenchymal stem cells using cDNA microarrays, and identified genes that were differentially expressed in specific stem cell populations. In particular we were able to identify potential hESC signature-like genes that encode transcription factors (TFAP2C and MYCN), an RNA binding protein (IMP-3), and a functionally uncharacterized protein (MAGEA4). The overlapping sets of 22 up-regulated and 141 downregulated genes identified in this study of three human stem cell types may also provide insight into the developmental mechanisms common to all human stem cells. Furthermore, our comprehensive analyses of gene expression profiles in various adult stem cells may help to identify the genetic pathways involved in self-renewal as well as in multi-lineage specific differentiation. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC MOLECULAR & CELLULAR BIOLOGY | - |
dc.title | Profiling of differentially expressed genes in human stem cells by cDNA microarray | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Chul Geun | - |
dc.contributor.affiliatedAuthor | Chat, Kyung Joon | - |
dc.identifier.scopusid | 2-s2.0-33745834792 | - |
dc.identifier.wosid | 000238843800004 | - |
dc.identifier.bibliographicCitation | MOLECULES AND CELLS, v.21, no.3, pp.343 - 355 | - |
dc.relation.isPartOf | MOLECULES AND CELLS | - |
dc.citation.title | MOLECULES AND CELLS | - |
dc.citation.volume | 21 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 343 | - |
dc.citation.endPage | 355 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001014437 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Cell Biology | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Cell Biology | - |
dc.subject.keywordPlus | MARROW STROMAL CELLS | - |
dc.subject.keywordPlus | MOLECULAR SIGNATURE | - |
dc.subject.keywordPlus | MOUSE | - |
dc.subject.keywordPlus | LINES | - |
dc.subject.keywordPlus | PLURIPOTENCY | - |
dc.subject.keywordPlus | REGENERATION | - |
dc.subject.keywordPlus | PROTEINS | - |
dc.subject.keywordPlus | PATTERNS | - |
dc.subject.keywordPlus | ANTIGEN | - |
dc.subject.keywordPlus | CLONING | - |
dc.subject.keywordAuthor | cDNA microarray | - |
dc.subject.keywordAuthor | expression profiling | - |
dc.subject.keywordAuthor | human CD34(+) | - |
dc.subject.keywordAuthor | hematopoietic stem/progenitor cells | - |
dc.subject.keywordAuthor | human CD133(+) hematopoietic | - |
dc.subject.keywordAuthor | stem/progenitor cells | - |
dc.subject.keywordAuthor | human embryonic stem cells | - |
dc.subject.keywordAuthor | human mesenchymal stem cells | - |
dc.subject.keywordAuthor | stem cell signature | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
222, Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea+82-2-2220-1365
COPYRIGHT © 2021 HANYANG UNIVERSITY.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.