Collagen scaffolds derived from a marine source and their biocompatibility
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Song, Eun | - |
dc.contributor.author | Kim,YeonSo | - |
dc.contributor.author | Chun, Taehoon | - |
dc.contributor.author | Byun, Hyun-Jung | - |
dc.contributor.author | Lee, Young Moo | - |
dc.date.accessioned | 2022-12-21T11:23:44Z | - |
dc.date.available | 2022-12-21T11:23:44Z | - |
dc.date.created | 2022-09-16 | - |
dc.date.issued | 2006-05 | - |
dc.identifier.issn | 0142-9612 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/181511 | - |
dc.description.abstract | The primary sources of industrial collagens are calf skin and bone. However, these carry a high risk of bovine spongiform encephalopathy or transmissible spongiform encephalopathy. In this Study, a novel form of acid-soluble collagen was extracted from jellyfish in an effort to obtain an alternative and safer collagen. Porous scaffolds composed of jellyfish collagen were prepared by freeze-drying and cross-linking with 1-ethyl-(3-3-dimethylaminopropyl) carbodiimide hydrochloride/N-hydroxysuccinimide to be used in tissue engineering applications. Enzymatic degradation kinetics of jellyfish collagen scaffolds were controlled by EDC/NHS-cross-linking density. Results from an MTT assay indicated that jellyfish collagen exhibited higher cell viability than other naturally derived biomaterials, including bovine collagen, gelatin, hyaluronic acid, and glucan. Jellyfish collagen scaffolds also had a highly porous and interconnected pore structure, Which is useful for an high-density cell seeding, Lin efficient nutrient and an oxygen supply to the cells cultured in the three-dimensional matrices. To determine whether jellyfish collagen evokes my specific inflammatory response compared to that induced by bovine collagen or gelatin, we measured the levels of pro-inflammatory cytokines and antibody secretions and monitored the population changes of immune cells after in vivo implantation. Jellyfish collagen was found to induce an immune response at least comparable to those caused by bovine collagen and gelatin. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCI LTD | - |
dc.title | Collagen scaffolds derived from a marine source and their biocompatibility | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Young Moo | - |
dc.identifier.doi | 10.1016/j.biomaterials.2006.01.015 | - |
dc.identifier.scopusid | 2-s2.0-32144435234 | - |
dc.identifier.wosid | 000236434000006 | - |
dc.identifier.bibliographicCitation | BIOMATERIALS, v.27, no.15, pp.2951 - 2961 | - |
dc.relation.isPartOf | BIOMATERIALS | - |
dc.citation.title | BIOMATERIALS | - |
dc.citation.volume | 27 | - |
dc.citation.number | 15 | - |
dc.citation.startPage | 2951 | - |
dc.citation.endPage | 2961 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalWebOfScienceCategory | Engineering, Biomedical | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Biomaterials | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | PHYSICOCHEMICAL PROPERTIES | - |
dc.subject.keywordPlus | SKIN COLLAGEN | - |
dc.subject.keywordPlus | CROSS-LINKING | - |
dc.subject.keywordPlus | TISSUE | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordPlus | BIOMATERIALS | - |
dc.subject.keywordPlus | CARTILAGE | - |
dc.subject.keywordPlus | DELIVERY | - |
dc.subject.keywordPlus | DESIGN | - |
dc.subject.keywordAuthor | collagen | - |
dc.subject.keywordAuthor | jellyfish | - |
dc.subject.keywordAuthor | scaffold | - |
dc.subject.keywordAuthor | tissue engineering | - |
dc.subject.keywordAuthor | immune response | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0142961206000147?via%3Dihub | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
222, Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea+82-2-2220-1365
COPYRIGHT © 2021 HANYANG UNIVERSITY.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.