Structural and biological characterization of sulfated-derivatized oat beta-glucan
DC Field | Value | Language |
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dc.contributor.author | Chang, Yun Jeoung | - |
dc.contributor.author | Lee, Suyong | - |
dc.contributor.author | Yoo, Mi Ae | - |
dc.contributor.author | Lee, Hyeon Gyu | - |
dc.date.accessioned | 2022-12-21T11:34:20Z | - |
dc.date.available | 2022-12-21T11:34:20Z | - |
dc.date.created | 2022-09-16 | - |
dc.date.issued | 2006-05 | - |
dc.identifier.issn | 0021-8561 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/181525 | - |
dc.description.abstract | The structural, physicochemical, and biological properties of sulfated oat beta-glucan were characterized. The degree of substitution of the sulfated oat-beta glucan was obtained by elemental analysis, which was 0.68. Compared to native oat beta-glucan, the FT-IR spectra of the derivative showed two new absorption bands at 1250 and 810 cm(-1), which would be attributed to (S = O) and (C-O-S) groups, respectively. The molecular weight of the sulfated beta-glucan was determined to be 68 kDa and its viscosity decreased by almost 2 orders of magnitude while its solubility increased by more than 100% compared to that of the native beta-glucan. In addition, the sulfation caused the reduction of in vitro bile acid binding capacity of oat beta-glucan due to the new anionic character and decreased molecular weight. The sulfated derivative exhibited, however, anticoagulant activity which showed a concentration-dependent increase. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.title | Structural and biological characterization of sulfated-derivatized oat beta-glucan | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Hyeon Gyu | - |
dc.identifier.doi | 10.1021/jf060243w | - |
dc.identifier.scopusid | 2-s2.0-33745506036 | - |
dc.identifier.wosid | 000237832100009 | - |
dc.identifier.bibliographicCitation | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, v.54, no.11, pp.3815 - 3818 | - |
dc.relation.isPartOf | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | - |
dc.citation.title | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | - |
dc.citation.volume | 54 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 3815 | - |
dc.citation.endPage | 3818 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Agriculture | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Food Science & Technology | - |
dc.relation.journalWebOfScienceCategory | Agriculture, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Applied | - |
dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
dc.subject.keywordPlus | ANTITUMOR ACTIVITIES | - |
dc.subject.keywordPlus | ANTICOAGULANT | - |
dc.subject.keywordPlus | ACID | - |
dc.subject.keywordPlus | RAT | - |
dc.subject.keywordAuthor | oat beta-glucan | - |
dc.subject.keywordAuthor | sulfation | - |
dc.subject.keywordAuthor | bile acid | - |
dc.subject.keywordAuthor | anticoagulant activity | - |
dc.identifier.url | https://pubs.acs.org/doi/10.1021/jf060243w | - |
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