Minimizing susceptibility-induced BOLD sensitivity loss in multi-band accelerated fMRI using point spread function mapping and gradient reversal
DC Field | Value | Language |
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dc.contributor.author | In, Myung-Ho | - |
dc.contributor.author | Kang, Daehun | - |
dc.contributor.author | Jo, Hang Joon | - |
dc.contributor.author | Yarach, Uten | - |
dc.contributor.author | Meyer, Nolan K. | - |
dc.contributor.author | Trzasko, Joshua D. | - |
dc.contributor.author | Huston III, John | - |
dc.contributor.author | Bernstein, Matt A. | - |
dc.contributor.author | Shu, Yunhong | - |
dc.date.accessioned | 2023-02-21T05:31:02Z | - |
dc.date.available | 2023-02-21T05:31:02Z | - |
dc.date.created | 2023-02-08 | - |
dc.date.issued | 2023-01 | - |
dc.identifier.issn | 0031-9155 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/182344 | - |
dc.description.abstract | Objective. Interleaved reverse-gradient fMRI (RG-fMRI) with a point-spread-function (PSF) mapping-based distortion correction scheme has the potential to minimize signal loss in echo-planar-imaging (EPI). In this work, the RG-fMRI is further improved by imaging protocol optimization and application of reverse Fourier acquisition. Approach. Multi-band imaging was adapted for RG-fMRI to improve the temporal and spatial resolution. To better understand signal dropouts in forward and reverse EPIs, a simple theoretical relationship between echo shift and geometric distortion was derived and validated by the reliable measurements using PSF mapping method. After examining practical imaging protocols for RG-fMRI in three subjects on both a conventional whole-body and a high-performance compact 3 T, the results were compared and the feasibility to further improve the RG-fMRI scheme were explored. High-resolution breath-holding RG-fMRI was conducted with nine subjects on the compact 3 T and the fMRI reliability improvement in high susceptibility brain regions was demonstrated. Finally, reverse Fourier acquisition was applied to RG-fMRI, and its benefit was assessed by a simulation study based on the breath-holding RG-fMRI data. Main results. The temporal and spatial resolution of the multi-band RG-fMRI became feasible for whole-brain fMRI. Echo shift measurements from PSF mapping well estimated signal dropout effects in the EPI pair and were useful to further improve the RG-fMRI scheme. Breath-holding RG-fMRI demonstrated improved fMRI reliability in high susceptibility brain regions. Reverse partial Fourier acquisition omitting the late echoes could further improve the temporal or spatial resolution for RG-fMRI without noticeable signal degradation and spatial resolution loss. Significance. With the improved imaging scheme, RG-fMRI could reliably investigate the functional mechanisms of the human brain in the temporal and frontal areas suffering from susceptibility-induced functional sensitivity loss. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | IOP Publishing Ltd | - |
dc.title | Minimizing susceptibility-induced BOLD sensitivity loss in multi-band accelerated fMRI using point spread function mapping and gradient reversal | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Jo, Hang Joon | - |
dc.identifier.doi | 10.1088/1361-6560/acae14 | - |
dc.identifier.scopusid | 2-s2.0-85145956294 | - |
dc.identifier.wosid | 000911346800001 | - |
dc.identifier.bibliographicCitation | PHYSICS IN MEDICINE AND BIOLOGY, v.68, no.2, pp.1 - 13 | - |
dc.relation.isPartOf | PHYSICS IN MEDICINE AND BIOLOGY | - |
dc.citation.title | PHYSICS IN MEDICINE AND BIOLOGY | - |
dc.citation.volume | 68 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 13 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Engineering, Biomedical | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.subject.keywordPlus | DISTORTION | - |
dc.subject.keywordPlus | EPI | - |
dc.subject.keywordPlus | RECONSTRUCTION | - |
dc.subject.keywordPlus | MEMORY | - |
dc.subject.keywordAuthor | point spread function | - |
dc.subject.keywordAuthor | reverse gradient approach | - |
dc.subject.keywordAuthor | susceptibility artifacts | - |
dc.subject.keywordAuthor | EPI distortion | - |
dc.subject.keywordAuthor | geometric distortion | - |
dc.subject.keywordAuthor | signal loss | - |
dc.identifier.url | https://iopscience.iop.org/article/10.1088/1361-6560/acae14 | - |
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