Rewiring of metabolic pathways in yeasts for sustainable production of biofuels
- Authors
- Maurya, Rupesh; Gohil, Nisarg; Nixon, Snovia; Kumar, Nilesh; Noronha, Santosh B.; Dhali, Debarun; Trabelsi, Heykel; Alzahrani, Khalid J.; Reshamwala, Shamlan M.S.; Awasthi, Mukesh Kumar; Ramakrishna, Suresh; Singh, Vijai
- Issue Date
- Mar-2023
- Publisher
- Elsevier Ltd
- Keywords
- Biofuels; Fatty acids; Metabolic engineering; Microbial cell factories; Yeast
- Citation
- Bioresource Technology, v.372, pp.1 - 11
- Indexed
- SCIE
SCOPUS
- Journal Title
- Bioresource Technology
- Volume
- 372
- Start Page
- 1
- End Page
- 11
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/182453
- DOI
- 10.1016/j.biortech.2023.128668
- ISSN
- 0960-8524
- Abstract
- The ever-increasing global energy demand has led world towards negative repercussions such as depletion of fossil fuels, pollution, global warming and climate change. Designing microbial cell factories for the sustainable production of biofuels is therefore an active area of research. Different yeast cells have been successfully engineered using synthetic biology and metabolic engineering approaches for the production of various biofuels. In the present article, recent advancements in genetic engineering strategies for production of bioalcohols, isoprenoid-based biofuels and biodiesels in different yeast chassis designs are reviewed, along with challenges that must be overcome for efficient and high titre production of biofuels.
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