Comparison of Three Cardiovascular Risk Scores among HIV-Infected Patients in Korea: The Korea HIV/AIDS Cohort Study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Bae, Ji Yun | - |
dc.contributor.author | Kim, Soo Min | - |
dc.contributor.author | Choi, Yunsu | - |
dc.contributor.author | Choi, Jun Yong | - |
dc.contributor.author | Kim, Sang Il | - |
dc.contributor.author | Kim, Shin-Woo | - |
dc.contributor.author | Park, Bo Young | - |
dc.contributor.author | Choi, Bo Youl | - |
dc.contributor.author | Choi, Hee Jung | - |
dc.date.accessioned | 2023-06-01T06:57:21Z | - |
dc.date.available | 2023-06-01T06:57:21Z | - |
dc.date.created | 2022-10-06 | - |
dc.date.issued | 2022-09 | - |
dc.identifier.issn | 2093-2340 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/185818 | - |
dc.description.abstract | Background We investigated cardiovascular disease (CVD), risk factors for CVD, and applicability of the three known CVD risk equations in the Korean human immunodeficiency virus/ Acquired Immune Deficiency Syndrome (HIV/AIDS) cohort. Materials and Methods The study parcitipants were HIV-infected patients in a Korean HIV/AIDS cohort enrolled from 19 hospitals between 2006 and 2017. Data collected at entry to the cohort were analyzed. The 5-year CVD risk in each participant was calculated using three CVD risk equations: reduced CVD prediction model of HIV-specific data collection on adverse effects of anti-HIV drugs (R-DAD), Framingham general CVD risk score (FRS), and Korean Coronary Heart Disease Risk Score (KRS). Results CVD events were observed in 11 of 586 HIV-infected patients during a 5-year (median) follow-up period. The incidence of CVD was 4.11 per 1,000 person-years. Older age (64 vs. 41 years, P = 0.005) and diabetes mellitus (45.5% vs. 6.4%, P <0.001) were more frequent in patients with CVD. Using R-DAD, FRS, and KRS, 1.9%, 2.4%, and 0.7% of patients, respectively, were considered to have a very high risk (≥10%) of 5-year CVD. The discriminatory capacities of the three prediction models were good, with c-statistic values of 0.829 (P <0.001) for R-DAD, 0.824 (P <0.001) for FRS, and 0.850 (P = 0.001) for KRS. Conclusion The FRS, R-DAD, and KRS performed well in the Korean HIV/AIDS cohort. A larger cohort and a longer period of follow-up may be necessary to demonstrate the risk factors and develop an independent CVD risk prediction model specific to Korean patients with HIV. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Korean Society of Infectious Diseases, Korean Society for Antimicrobial Therapy, Korean Society for AIDS | - |
dc.title | Comparison of Three Cardiovascular Risk Scores among HIV-Infected Patients in Korea: The Korea HIV/AIDS Cohort Study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Park, Bo Young | - |
dc.contributor.affiliatedAuthor | Choi, Bo Youl | - |
dc.identifier.doi | 10.3947/ic.2022.0048 | - |
dc.identifier.scopusid | 2-s2.0-85137414341 | - |
dc.identifier.wosid | 000875636600002 | - |
dc.identifier.bibliographicCitation | Infection and Chemotherapy, v.54, no.3, pp.409 - 418 | - |
dc.relation.isPartOf | Infection and Chemotherapy | - |
dc.citation.title | Infection and Chemotherapy | - |
dc.citation.volume | 54 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 409 | - |
dc.citation.endPage | 418 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002884781 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Infectious Diseases | - |
dc.relation.journalWebOfScienceCategory | Infectious Diseases | - |
dc.subject.keywordPlus | ANTIRETROVIRAL THERAPY | - |
dc.subject.keywordPlus | VIRAL REPLICATION | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | FRAMINGHAM | - |
dc.subject.keywordPlus | INTERRUPTION | - |
dc.subject.keywordAuthor | HIV | - |
dc.subject.keywordAuthor | Korea | - |
dc.subject.keywordAuthor | Cardiovascular diseases | - |
dc.subject.keywordAuthor | Coronary disease | - |
dc.identifier.url | https://icjournal.org/DOIx.php?id=10.3947/ic.2022.0048 | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
222, Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea+82-2-2220-1365
COPYRIGHT © 2021 HANYANG UNIVERSITY.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.