Role of Shear Wave Elastography in Evaluating the Risk of Hepatocellular Carcinoma in Patients with Chronic Hepatitis B
DC Field | Value | Language |
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dc.contributor.author | Jeong, Jae Yoon | - |
dc.contributor.author | Sohn, Joo Hyun | - |
dc.contributor.author | Sohn, Won | - |
dc.contributor.author | Park, Chan Hyuk | - |
dc.contributor.author | Kim, Tae Yeob | - |
dc.contributor.author | Jun, Dae Won | - |
dc.contributor.author | Kim, Yongsoo | - |
dc.contributor.author | Jeong, Woo Kyoung | - |
dc.date.accessioned | 2021-08-02T14:28:33Z | - |
dc.date.available | 2021-08-02T14:28:33Z | - |
dc.date.created | 2021-05-11 | - |
dc.date.issued | 2017-11 | - |
dc.identifier.issn | 1976-2283 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/18687 | - |
dc.description.abstract | Background/Aims: To investigate the use of measurements of liver stiffness (LS) by two-dimensional real-time shear wave elastography (SWE) for predicting the development of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B (CHB). Methods: We retrospectively collected data on 291 enrolled patients with CHB whose LS had been measured using SWE. Results: The mean age of the patients was 46.8 years; males predominated (67%), and 40 of the patients (14%) had clinical cirrhosis. Among the patients, 165 (56.7%) received antiviral treatment. The median LS value was 7.4 kPa, and the median follow-up period was 35.8 months (range, 3.0 to 52.8 months). During follow-up, HCC developed in 13 patients (4.5%), and the cumulative incidence rates of HCC at 1, 2, and 4 years were 1.1%, 3.6%, and 8.4%, respectively. Based on a multivariate analysis, older age (>= 50 years) and higher LS value (>= 10 kPa) were independently associated with the risk of developing HCC (hazard ratio [HR], 4.53, p=0.023; and HR, 4.08, p=0.022). The cumulative incidence rate of HCC was significantly higher in patients with higher LS values (>= 10 kPa) than in those with lower LS values (< 10 kPa) (p=0.001). Conclusions: Increased LS measured by SWE at any time point regardless of antiviral treatment is associated with an increased risk of HCC in patients with CHB. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | EDITORIAL OFFICE GUT & LIVER | - |
dc.title | Role of Shear Wave Elastography in Evaluating the Risk of Hepatocellular Carcinoma in Patients with Chronic Hepatitis B | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Sohn, Joo Hyun | - |
dc.contributor.affiliatedAuthor | Park, Chan Hyuk | - |
dc.contributor.affiliatedAuthor | Jun, Dae Won | - |
dc.contributor.affiliatedAuthor | Kim, Yongsoo | - |
dc.identifier.doi | 10.5009/gnl16521 | - |
dc.identifier.scopusid | 2-s2.0-85038935323 | - |
dc.identifier.wosid | 000414775200017 | - |
dc.identifier.bibliographicCitation | GUT AND LIVER, v.11, no.6, pp.852 - 859 | - |
dc.relation.isPartOf | GUT AND LIVER | - |
dc.citation.title | GUT AND LIVER | - |
dc.citation.volume | 11 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 852 | - |
dc.citation.endPage | 859 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002283195 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.subject.keywordPlus | LIVER FIBROSIS | - |
dc.subject.keywordPlus | TRANSIENT ELASTOGRAPHY | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | PERFORMANCE | - |
dc.subject.keywordPlus | STIFFNESS | - |
dc.subject.keywordPlus | BIOPSY | - |
dc.subject.keywordPlus | INFECTION | - |
dc.subject.keywordPlus | CIRRHOSIS | - |
dc.subject.keywordPlus | ACCURACY | - |
dc.subject.keywordPlus | COHORT | - |
dc.subject.keywordAuthor | Elastography | - |
dc.subject.keywordAuthor | shear wave | - |
dc.subject.keywordAuthor | Liver stiffness | - |
dc.subject.keywordAuthor | Hepatitis B | - |
dc.subject.keywordAuthor | chronic | - |
dc.subject.keywordAuthor | Carcinoma | - |
dc.subject.keywordAuthor | hepatocellular | - |
dc.identifier.url | https://www.gutnliver.org/journal/view.html?doi=10.5009/gnl16521 | - |
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