The relationship between long-term use of nonsteroidal anti-inflammatory drugs and kidney function in patients with ankylosing spondylitis
DC Field | Value | Language |
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dc.contributor.author | Koo, Bon San | - |
dc.contributor.author | Hwang, Subin | - |
dc.contributor.author | Park, Seo Young | - |
dc.contributor.author | Shin, Ji Hui | - |
dc.contributor.author | Kim, Tae-Hwan | - |
dc.date.accessioned | 2023-07-24T08:30:01Z | - |
dc.date.available | 2023-07-24T08:30:01Z | - |
dc.date.created | 2023-05-03 | - |
dc.date.issued | 2023-04 | - |
dc.identifier.issn | 2093-940X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/187247 | - |
dc.description.abstract | Objective: Although nonsteroidal anti-inflammatory drugs (NSAIDs) are the first-line treatment for ankylosing spondylitis (AS), their effect on kidney function remains unclear. This longitudinal study investigated the correlation between long-term NSAID use and kidney function in patients with AS using electronic medical records. Methods: The electronic medical records of 1,280 patients with AS collected from a single center between January 2001 and De-cember 2018 were reviewed. The Assessment of Spondyloarthritis International Society (ASAS) NSAID Intake Score was used to determine the cumulative dose of all NSAIDs prescribed for a different time intervals. Each ASAS NSAID Intake Score was obtained for intervals of 6 months, 1 year, 2 years, 3 years, 5 years, and 10 years. The correlation between the ASAS NSAID Intake Score and final estimated glomerular filtration rate (eGFR) for each interval was investigated. Results: The mean ASAS Intake Scores for 6-month, 1-year, 2-year, 3-year, 5-year, and 10-year intervals were 55.30, 49.28, 44.84, 44.14, 44.61, and 41.17, respectively. At each interval, the pearson correlation coefficients were -0.018 (95% CI: -0.031 to -0.006, p=0.004), -0.021 (95% CI: -0.039 to -0.004, p=0.018), -0.045 (95% CI: -0.071 to -0.019, p=0.001), -0.069 (95% CI: -0.102 to -0.037, p<0.001), -0.070 (95% CI: -0.114 to -0.026, p=0.002), -0.019 (95% CI: -0.099 to 0.062, p=0.645), respectively. There was a very weak negative relationship between ASAS Intake Score and eGFR at each interval. Conclusion: Long-term NSAID use did not correlate with kidney function based on real-world data in patients with AS. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN COLL RHEUMATOLOGY | - |
dc.title | The relationship between long-term use of nonsteroidal anti-inflammatory drugs and kidney function in patients with ankylosing spondylitis | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Tae-Hwan | - |
dc.identifier.doi | 10.4078/jrd.2023.0006 | - |
dc.identifier.scopusid | 2-s2.0-85162757363 | - |
dc.identifier.wosid | 000962013800007 | - |
dc.identifier.bibliographicCitation | JOURNAL OF RHEUMATIC DISEASES, v.30, no.2, pp.126 - 132 | - |
dc.relation.isPartOf | JOURNAL OF RHEUMATIC DISEASES | - |
dc.citation.title | JOURNAL OF RHEUMATIC DISEASES | - |
dc.citation.volume | 30 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 126 | - |
dc.citation.endPage | 132 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002941699 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Rheumatology | - |
dc.relation.journalWebOfScienceCategory | Rheumatology | - |
dc.subject.keywordPlus | PROGRESSION | - |
dc.subject.keywordPlus | NSAIDS | - |
dc.subject.keywordAuthor | Anti-inflammatory agents | - |
dc.subject.keywordAuthor | non-steroidal | - |
dc.subject.keywordAuthor | Kidney function tests | - |
dc.subject.keywordAuthor | Renal insufficiency | - |
dc.subject.keywordAuthor | chronic | - |
dc.subject.keywordAuthor | Spondylitis | - |
dc.subject.keywordAuthor | ankylosing | - |
dc.identifier.url | https://www.jrd.or.kr/journal/view.html?doi=10.4078/jrd.2023.0006 | - |
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