Mesoporous platinum nanozyme-based competitive immunoassay for sensitive detection of 25-hydroxyvitamin D
DC Field | Value | Language |
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dc.contributor.author | Lee, Han Been | - |
dc.contributor.author | Son, Seong Eun | - |
dc.contributor.author | Gupta, Pramod K. | - |
dc.contributor.author | Venkatesan, Jayachandran | - |
dc.contributor.author | Hur, Won | - |
dc.contributor.author | Park, Jiyeon | - |
dc.contributor.author | Kim, Seong Nyeon | - |
dc.contributor.author | Seong, Gi Hun | - |
dc.date.accessioned | 2023-07-24T10:08:39Z | - |
dc.date.available | 2023-07-24T10:08:39Z | - |
dc.date.created | 2022-11-09 | - |
dc.date.issued | 2023-01 | - |
dc.identifier.issn | 0167-577X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/187609 | - |
dc.description.abstract | In this study, mesoporous platinum nanozymes (MPNs) were fabricated by a surfactant-based self-assembly method and then used to develop a novel competitive immunoassay for sensitive detection of 25-hydroxyvitamin D3 (25(OH)VD3). The MPNs showed enhanced peroxidase-like activity that catalyzes the reaction between hydrogen peroxide (H2O2) and 3,3 ',5,5 '-tetramethylbenzidine (TMB). The excellent peroxidase-like MPNs were employed to develop a competitive immunoassay for the sensitive colorimetric detection of 25(OH)VD3. The immunoassay detected 25(OH)VD3 in the range of 1.6 to 100 ng/mL, with a detection limit of 1.0 ng/mL. The recovery values of 25(OH)VD3 from the spiked human serum samples were between 104% and 95%. These results indicate the applicability of MPNs as alternatives for natural enzymes and the feasibility for sensitive 25 (OH)VD3 detection. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER | - |
dc.title | Mesoporous platinum nanozyme-based competitive immunoassay for sensitive detection of 25-hydroxyvitamin D | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Seong, Gi Hun | - |
dc.identifier.doi | 10.1016/j.matlet.2022.133286 | - |
dc.identifier.scopusid | 2-s2.0-85139390514 | - |
dc.identifier.wosid | 000868565300001 | - |
dc.identifier.bibliographicCitation | MATERIALS LETTERS, v.330 | - |
dc.relation.isPartOf | MATERIALS LETTERS | - |
dc.citation.title | MATERIALS LETTERS | - |
dc.citation.volume | 330 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.subject.keywordPlus | VITAMIN-D | - |
dc.subject.keywordAuthor | Vitamin D | - |
dc.subject.keywordAuthor | Nanozymes | - |
dc.subject.keywordAuthor | Mesoporous nanoparticles | - |
dc.subject.keywordAuthor | Competitive immunoassay | - |
dc.subject.keywordAuthor | Colorimetry | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0167577X2201641X?via%3Dihub | - |
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