A comprehensive appraisal of mechanism of anti-CRISPR proteins: an advanced genome editor to amend the CRISPR gene editing
DC Field | Value | Language |
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dc.contributor.author | Choudhary, Nisha | - |
dc.contributor.author | Tandi, Dipty | - |
dc.contributor.author | Verma, Rakesh Kumar | - |
dc.contributor.author | Yadav, Virendra Kumar | - |
dc.contributor.author | Dhingra, Naveen | - |
dc.contributor.author | Ghosh, Tathagata | - |
dc.contributor.author | Choudhary, Mahima | - |
dc.contributor.author | Gaur, Rajarshi K. K. | - |
dc.contributor.author | Abdellatif, Magda H. H. | - |
dc.contributor.author | Gacem, Amel | - |
dc.contributor.author | Eltayeb, Lienda Bashier | - |
dc.contributor.author | Alqahtani, Mohammed S. S. | - |
dc.contributor.author | Yadav, Krishna Kumar | - |
dc.contributor.author | Jeon, Byong-Hun | - |
dc.date.accessioned | 2023-08-01T06:35:17Z | - |
dc.date.available | 2023-08-01T06:35:17Z | - |
dc.date.created | 2023-07-25 | - |
dc.date.issued | 2023-06 | - |
dc.identifier.issn | 1664-462X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/188402 | - |
dc.description.abstract | The development of precise and controlled CRISPR-Cas tools has been made possible by the discovery of protein inhibitors of CRISPR-Cas systems, called anti-CRISPRs (Acrs). The Acr protein has the ability to control off-targeted mutations and impede Cas protein-editing operations. Acr can help with selective breeding, which could help plants and animals improve their valuable features. In this review, the Acr protein-based inhibitory mechanisms that have been adopted by several Acrs, such as (a) the interruption of CRISPR-Cas complex assembly, (b) interference with target DNA binding, (c) blocking of target DNA/RNA cleavage, and (d) enzymatic modification or degradation of signalling molecules, were discussed. In addition, this review emphasizes the applications of Acr proteins in the plant research. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | FRONTIERS MEDIA SA | - |
dc.title | A comprehensive appraisal of mechanism of anti-CRISPR proteins: an advanced genome editor to amend the CRISPR gene editing | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Jeon, Byong-Hun | - |
dc.identifier.doi | 10.3389/fpls.2023.1164461 | - |
dc.identifier.scopusid | 2-s2.0-85165028218 | - |
dc.identifier.wosid | 001023767500001 | - |
dc.identifier.bibliographicCitation | FRONTIERS IN PLANT SCIENCE, v.14, pp.1 - 14 | - |
dc.relation.isPartOf | FRONTIERS IN PLANT SCIENCE | - |
dc.citation.title | FRONTIERS IN PLANT SCIENCE | - |
dc.citation.volume | 14 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 14 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Plant Sciences | - |
dc.relation.journalWebOfScienceCategory | Plant Sciences | - |
dc.subject.keywordPlus | VIRAL SUPPRESSORS | - |
dc.subject.keywordPlus | RNA | - |
dc.subject.keywordPlus | INHIBITION | - |
dc.subject.keywordPlus | DNA | - |
dc.subject.keywordPlus | BINDING | - |
dc.subject.keywordAuthor | anti-CRISPR | - |
dc.subject.keywordAuthor | genome editing | - |
dc.subject.keywordAuthor | Acr inhibitors | - |
dc.subject.keywordAuthor | genetic memory | - |
dc.subject.keywordAuthor | CRISPR-Cas complex | - |
dc.subject.keywordAuthor | DNA binding inhibition | - |
dc.subject.keywordAuthor | DNA cleavage | - |
dc.identifier.url | https://www.frontiersin.org/articles/10.3389/fpls.2023.1164461/full | - |
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