A visuomotor circuit for evasive flight turns in Drosophila
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Hyosun | - |
dc.contributor.author | Park, Hayun | - |
dc.contributor.author | Lee, Joowon | - |
dc.contributor.author | Kim, Anmo J. | - |
dc.date.accessioned | 2023-09-04T05:31:56Z | - |
dc.date.available | 2023-09-04T05:31:56Z | - |
dc.date.created | 2023-02-08 | - |
dc.date.issued | 2023-01 | - |
dc.identifier.issn | 0960-9822 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/189597 | - |
dc.description.abstract | Visual systems extract multiple features from a scene using parallel neural circuits. Ultimately, the separate neural signals must come together to coherently influence action. Here, we characterize a circuit in Drosophila that integrates multiple visual features related to imminent threats to drive evasive locomotor turns. We identified, using genetic perturbation methods, a pair of visual projection neurons (LPLC2) and descending neurons (DNp06) that underlie evasive flight turns in response to laterally moving or approaching visual objects. Using two-photon calcium imaging or whole-cell patch clamping, we show that these cells indeed respond to both translating and approaching visual patterns. Furthermore, by measuring visual responses of LPLC2 neurons after genetically silencing presynaptic motion-sensing neurons, we show that their visual properties emerge by integrating multiple visual features across two early visual structures: the lobula and the lobula plate. This study highlights a clear example of how distinct visual signals converge on a single class of visual neurons and then activate premotor neurons to drive action, revealing a concise visuomotor pathway for evasive flight maneuvers in Drosophila. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | CELL PRESS | - |
dc.title | A visuomotor circuit for evasive flight turns in Drosophila | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Anmo J. | - |
dc.identifier.doi | 10.1016/j.cub.2022.12.014 | - |
dc.identifier.scopusid | 2-s2.0-85146446307 | - |
dc.identifier.wosid | 001030022500001 | - |
dc.identifier.bibliographicCitation | CURRENT BIOLOGY, v.33, no.2, pp.321 - 335.e6 | - |
dc.relation.isPartOf | CURRENT BIOLOGY | - |
dc.citation.title | CURRENT BIOLOGY | - |
dc.citation.volume | 33 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 321 | - |
dc.citation.endPage | 335.e6 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Life Sciences & Biomedicine - Other Topics | - |
dc.relation.journalResearchArea | Cell Biology | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Biology | - |
dc.relation.journalWebOfScienceCategory | Cell Biology | - |
dc.subject.keywordPlus | NEURAL MECHANISMS | - |
dc.subject.keywordPlus | DETECTING NEURONS | - |
dc.subject.keywordPlus | INTEGRATION | - |
dc.subject.keywordPlus | FLY | - |
dc.subject.keywordPlus | INHIBITION | - |
dc.subject.keywordPlus | FRAMEWORK | - |
dc.subject.keywordPlus | BEHAVIOR | - |
dc.subject.keywordAuthor | descending neurons | - |
dc.subject.keywordAuthor | DNp06 | - |
dc.subject.keywordAuthor | Drosophila | - |
dc.subject.keywordAuthor | evasive flight turn | - |
dc.subject.keywordAuthor | LPLC2 | - |
dc.subject.keywordAuthor | threat detection | - |
dc.subject.keywordAuthor | visual projection neurons | - |
dc.subject.keywordAuthor | visuomotor circuit | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0960982222019145?via%3Dihub | - |
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