Value of discrepancy of the central scar-like structure between dynamic CT and gadoxetate disodium-enhanced MRI in differentiation of focal nodular hyperplasia and hepatocellular adenoma
DC Field | Value | Language |
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dc.contributor.author | Park, Hyo Jung | - |
dc.contributor.author | Byun, Jae Ho | - |
dc.contributor.author | Kang, Ji Hun | - |
dc.contributor.author | Kang, Hyo Jeong | - |
dc.contributor.author | Yu, Eunsil | - |
dc.contributor.author | Lee, So Jung | - |
dc.contributor.author | Kim, So Yeon | - |
dc.contributor.author | Won, Hyung Jin | - |
dc.contributor.author | Shin, Yong Moon | - |
dc.contributor.author | Kim, Pyo Nyun | - |
dc.date.accessioned | 2023-09-04T07:06:14Z | - |
dc.date.available | 2023-09-04T07:06:14Z | - |
dc.date.created | 2023-08-15 | - |
dc.date.issued | 2021-06 | - |
dc.identifier.issn | 0720-048X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/189648 | - |
dc.description.abstract | Purpose: To identify the value of discrepancies in the central scar (CS)-like structure between dynamic CT and gadoxetate disodium-enhanced MRI for differentiating FNH from HCA. Methods: This retrospective study included 113 patients with pathologically-diagnosed FNH (n = 80) or HCA (n = 37). CS-like structures were evaluated on arterial phase (AP) CT and hepatobiliary phase (HBP) MRI. Presence of the CS-like structure, its discrepancy in visibility or size between AP CT and HBP MRI and between AP and HBP MRI, and features of non-scarred tumor portion were evaluated by two radiologists. Inter-observer agreement was evaluated by intraclass correlation coefficients (ICCs) and weighted kappa. Univariable and multivariable logistic regression and ROC analysis were performed to explore features differentiating FNH from HCA. Results: Inter-observer agreement was moderate-to-excellent (ICCs≥0.74, kappa≥0.65). On univariable analysis, presence of CS-like structures (P < 0.001), discrepancy of the CS-like structures between AP CT and HBP MRI (73.8 % in FNH; 16.2 % in HCA, P < 0.001) and between AP and HBP MRI (70.0 % in FNH; 16.2 % in HCA, P < 0.001), and the features of non-scarred tumor portion (P ≤ 0.011) were significantly different between FNH and HCA. On multivariable analysis, the discrepancy of CS-like structures between AP CT and HBP MRI, and the absence of low SI of the non-scarred tumor portion on HBP MRI, were suggestive of FNH (P = 0.036 and P < 0.001, respectively; area under the ROC curve, 0.96 [95 % CI, 0.93–0.99]). Conclusion: Evaluation of discrepancy in the visibility or size of CS-like structures between dynamic CT and gadoxetate disodium-enhanced MRI may facilitate the differentiation of FNH from HCA. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Elsevier BV | - |
dc.title | Value of discrepancy of the central scar-like structure between dynamic CT and gadoxetate disodium-enhanced MRI in differentiation of focal nodular hyperplasia and hepatocellular adenoma | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kang, Ji Hun | - |
dc.identifier.doi | 10.1016/j.ejrad.2021.109730 | - |
dc.identifier.scopusid | 2-s2.0-85105835200 | - |
dc.identifier.wosid | 000649653000004 | - |
dc.identifier.bibliographicCitation | European Journal of Radiology, v.139, pp.1 - 8 | - |
dc.relation.isPartOf | European Journal of Radiology | - |
dc.citation.title | European Journal of Radiology | - |
dc.citation.volume | 139 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 8 | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.subject.keywordPlus | CLASSIFICATION | - |
dc.subject.keywordPlus | SUBTYPE | - |
dc.subject.keywordPlus | LIVER | - |
dc.subject.keywordPlus | FNH | - |
dc.subject.keywordAuthor | Adenoma | - |
dc.subject.keywordAuthor | Computed tomography | - |
dc.subject.keywordAuthor | Focal nodular hyperplasia | - |
dc.subject.keywordAuthor | Liver cell | - |
dc.subject.keywordAuthor | Magnetic resonance imaging | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0720048X21002102?via%3Dihub | - |
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