비타민 D의 자가면역, 알레르기, 감염질환에서의 역할Vitamin D in autoimmune, allergic, and infectious diseases
- Other Titles
- Vitamin D in autoimmune, allergic, and infectious diseases
- Authors
- 심채현; 최제민
- Issue Date
- Sep-2022
- Publisher
- 한국식품과학회
- Keywords
- vitamin D; immune system; autoimmune; allergy; infection
- Citation
- 식품과학과 산업, v.55, no.3, pp.276 - 283
- Indexed
- KCI
- Journal Title
- 식품과학과 산업
- Volume
- 55
- Number
- 3
- Start Page
- 276
- End Page
- 283
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/190087
- DOI
- 10.23093/FSI.2022.55.3.276
- ISSN
- 0257-2397
- Abstract
- Vitamin D is a fat-soluble vitamin helps to retain calcium and phosphorus but also has shown to affect immune regulation and homeostasis. In humans, vitamin D3 and vitamin D2 and their metabolite has intensively studied in both innate and adaptive immune system that they are important to regulate overwhelmed inflammation.
The vitamin D receptor is a nuclear hormone receptor which regulate various downstream target gene expressions as a transcription factor related to metabolism, immune regulation, etc. Vitamin D deficiency is a high-risk factor for inflammatory diseases like autoimmune disease and allergy. In addition, reduced vitamin D seem to correlate with susceptibility to the virus infection such as HIV and COVID-19. In this review, we will summarize up-to-date vitamin D’s role in various immune cells, immune regulatory functions during autoimmune, allergic, and infectious diseases. We will also discuss about vitamin D supplement effects in human trial studies for COVID-19.
- Files in This Item
-
Go to Link
- Appears in
Collections - 서울 자연과학대학 > 서울 생명과학과 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/190087)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.