Risk factors for herpes zoster in patients with rheumatic diseases: a nationwide cohort study in Korea
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ryu, Hee Jung | - |
dc.contributor.author | Han, Jin-Ok | - |
dc.contributor.author | Lee, Sang Ah | - |
dc.contributor.author | Seo, Mi Ryoung | - |
dc.contributor.author | Choi, Hyo Jin | - |
dc.contributor.author | Ko, Kwang-Pil | - |
dc.contributor.author | Baek, Han Joo | - |
dc.date.accessioned | 2023-09-11T01:49:52Z | - |
dc.date.available | 2023-09-11T01:49:52Z | - |
dc.date.created | 2023-07-21 | - |
dc.date.issued | 2021-05 | - |
dc.identifier.issn | 1462-0324 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/190360 | - |
dc.description.abstract | Objective. To determine the risk factors for herpes zoster (HZ) in patients with rheumatic diseases in Korea. Methods. We used the nationwide database of the Health Insurance Review & Assessment Service to analyse patients aged >20 years who had visited a hospital more than twice for rheumatic disease as a principal diagnosis from January 2009 to April 2013. HZ was identified using HZ-related Korean Standard Classification of Diseases 6 (KCD-6) codes and the prescription of antiviral agents. The relationship between demographics, comorbidities and medications and HZ risk was analysed by Cox proportional hazards models. Results. HZ developed in 1869 patients. In Cox proportional hazards models, female sex but not age showed an increased adjusted hazard ratio (HR) for HZ. Comorbidities such as haematologic malignancies, hypertension, diabetes mellitus, and chronic lung and liver diseases led to an increased HR. HZ risk was higher in patients with SLE (HR: 4.29, 95% CI: 3.49, 5.27) and Behcet's syndrome (BS, HR: 4.54; 95% CI: 3.66, 5.64) than with RA. The use of conventional DMARDs, immunosuppressants, TNF inhibitors, glucocorticoids and NSAIDs increased the HR. Infliximab and glucocorticoids (equivalent prednisolone dose >15 mg/day) produced the highest HZ risk (HR: 2.91, 95% CI: 1.72, 4.89; HR: 2.85, 95% CI: 2.15, 3.77, respectively). Conclusion. Female sex, comorbidities and medications increased HZ risk in patients with rheumatic diseases and even young patients could develop HZ. Compared with RA, SLE and BS are stronger HZ risk factors. Patients with rheumatic diseases and these risk factors are potential target populations for HZ vaccination. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | OXFORD UNIV PRESS | - |
dc.title | Risk factors for herpes zoster in patients with rheumatic diseases: a nationwide cohort study in Korea | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Ryu, Hee Jung | - |
dc.identifier.doi | 10.1093/rheumatology/keaa636 | - |
dc.identifier.scopusid | 2-s2.0-85107084236 | - |
dc.identifier.wosid | 000807554700046 | - |
dc.identifier.bibliographicCitation | RHEUMATOLOGY, v.60, no.5, pp.2427 - 2433 | - |
dc.relation.isPartOf | RHEUMATOLOGY | - |
dc.citation.title | RHEUMATOLOGY | - |
dc.citation.volume | 60 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 2427 | - |
dc.citation.endPage | 2433 | - |
dc.type.rims | ART | - |
dc.type.docType | 정기학술지(Article(Perspective Article포함)) | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Rheumatology | - |
dc.relation.journalWebOfScienceCategory | Rheumatology | - |
dc.subject.keywordPlus | NECROSIS-FACTOR-ALPHA | - |
dc.subject.keywordPlus | VARICELLA | - |
dc.subject.keywordPlus | ARTHRITIS | - |
dc.subject.keywordPlus | VIRUS | - |
dc.subject.keywordPlus | ASSOCIATIONS | - |
dc.subject.keywordPlus | SKIN | - |
dc.subject.keywordAuthor | risk factor | - |
dc.subject.keywordAuthor | herpes zoster | - |
dc.subject.keywordAuthor | rheumatic diseases | - |
dc.identifier.url | https://academic.oup.com/rheumatology/article/60/5/2427/6000239 | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
222, Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea+82-2-2220-1365
COPYRIGHT © 2021 HANYANG UNIVERSITY.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.