Normothermia in Patients With Sepsis Who Present to Emergency Departments Is Associated With Low Compliance With Sepsis Bundles and Increased In-Hospital Mortality Rate*
DC Field | Value | Language |
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dc.contributor.author | Park, Sunghoon | - |
dc.contributor.author | Jeon, Kyeongman | - |
dc.contributor.author | Oh, Dong Kyu | - |
dc.contributor.author | Choi, Eun Young | - |
dc.contributor.author | Seong, Gil Myeong | - |
dc.contributor.author | Heo, Jeongwon | - |
dc.contributor.author | Chang, Youjin | - |
dc.contributor.author | Kwack, Won Gun | - |
dc.contributor.author | Kang, Byung Ju | - |
dc.contributor.author | Choi, Wonil | - |
dc.contributor.author | Kim, Kyung Chan | - |
dc.contributor.author | Park, So Young | - |
dc.contributor.author | Shin, Yoon Mi | - |
dc.contributor.author | Lee,Heung Bum | - |
dc.contributor.author | Park, So Hee | - |
dc.contributor.author | Kim, Seok Chan | - |
dc.contributor.author | Kwak, Sang Hyun | - |
dc.contributor.author | Cho, Jae Hwa | - |
dc.contributor.author | Kim, Beongki | - |
dc.contributor.author | Lim, Chae-Man | - |
dc.date.accessioned | 2023-09-11T02:02:12Z | - |
dc.date.available | 2023-09-11T02:02:12Z | - |
dc.date.created | 2023-07-19 | - |
dc.date.issued | 2020-10 | - |
dc.identifier.issn | 0090-3493 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/190459 | - |
dc.description.abstract | Objectives: To investigate the impact of normothermia on compliance with sepsis bundles and in-hospital mortality in patients with sepsis who present to emergency departments. Design: Retrospective multicenter observational study. Patients: Nineteen university-affiliated hospitals of the Korean Sepsis Alliance participated in this study. Data were collected regarding patients who visited emergency departments for sepsis during the 1-month period. The patients were divided into three groups based on their body temperature at the time of triage in the emergency department (i.e., hypothermia [< 36 degrees C] vs normothermia [36-38 degrees C] vs hyperthermia [> 38 degrees C]). Interventions: None. Measurements and Main Results: Of 64,021 patients who visited emergency departments, 689 with community-acquired sepsis were analyzed (182 hyperthermic, 420 normothermic, and 87 hypothermic patients). The rate of compliance with the total hour-1 bundle was lowest in the normothermia group (6.0% vs 9.3% in hyperthermia vs 13.8% in hypothermia group;p= 0.032), the rate for lactate measurement was lowest in the normothermia group (62.1% vs 73.1% vs 75.9%;p= 0.005), and the blood culture rate was significantly lower in the normothermia than in the hyperthermia group (p< 0.001). The in-hospital mortality rates in the hyperthermia, normothermia, and hypothermia groups were 8.5%, 20.6%, and 30.8%, respectively (p< 0.001), but there was no significant association between compliance with sepsis bundles and in-hospital mortality. However, in a multivariate analysis, compared with hyperthermia, normothermia was significantly associated with an increased in-hospital mortality (odds ratio, 2.472; 95% CI, 1.005-6.080). This association remained significant even after stratifying patients by median lactate level. Conclusions: Normothermia at emergency department triage was significantly associated with an increased risk of in-hospital mortality and a lower rate of compliance with the sepsis bundle. Despite several limitations, our findings suggest a need for new strategies to improve sepsis outcomes in this group of patients. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS &amp; WILKINS | - |
dc.title | Normothermia in Patients With Sepsis Who Present to Emergency Departments Is Associated With Low Compliance With Sepsis Bundles and Increased In-Hospital Mortality Rate* | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Choi, Wonil | - |
dc.identifier.doi | 10.1097/CCM.0000000000004493 | - |
dc.identifier.scopusid | 2-s2.0-85091054161 | - |
dc.identifier.wosid | 000573616600038 | - |
dc.identifier.bibliographicCitation | CRITICAL CARE MEDICINE, v.48, no.10, pp.1462 - 1470 | - |
dc.relation.isPartOf | CRITICAL CARE MEDICINE | - |
dc.citation.title | CRITICAL CARE MEDICINE | - |
dc.citation.volume | 48 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 1462 | - |
dc.citation.endPage | 1470 | - |
dc.type.rims | ART | - |
dc.type.docType | 정기학술지(Article(Perspective Article포함)) | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Critical Care Medicine | - |
dc.subject.keywordPlus | INFECTIOUS-DISEASES-SOCIETY | - |
dc.subject.keywordPlus | INTERNATIONAL CONSENSUS DEFINITIONS | - |
dc.subject.keywordPlus | SEPTIC SHOCK | - |
dc.subject.keywordPlus | CORE TEMPERATURE | - |
dc.subject.keywordPlus | HYPOTHERMIA | - |
dc.subject.keywordPlus | GUIDELINES | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | IMPACT | - |
dc.subject.keywordPlus | FEVER | - |
dc.subject.keywordPlus | OUTCOMES | - |
dc.subject.keywordAuthor | emergency department | - |
dc.subject.keywordAuthor | mortality | - |
dc.subject.keywordAuthor | normothermia | - |
dc.subject.keywordAuthor | sepsis bundles | - |
dc.identifier.url | https://journals.lww.com/ccmjournal/fulltext/2020/10000/normothermia_in_patients_with_sepsis_who_present.8.aspx | - |
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