Highly selective and sensitive detection of catecholamines using NaLuGdF4:Yb3+/Er3+ upconversion nanoparticles decorated with metal ions
- Authors
- Gerelkhuu, Zayakhuu; Jung, Dasom; Bui The Huy; Tawfik, Salah M.; Conte, Maxwell L.; Conte, Eric D.; Lee, Yong-Ill
- Issue Date
- Apr-2019
- Publisher
- ELSEVIER SCIENCE SA
- Keywords
- Catecholamines; Metal ion decorated; Upconversion nanoparticles; 1,2-ethanedithiol; Human urine
- Citation
- SENSORS AND ACTUATORS B-CHEMICAL, v.284, pp.172 - 178
- Indexed
- SCIE
SCOPUS
- Journal Title
- SENSORS AND ACTUATORS B-CHEMICAL
- Volume
- 284
- Start Page
- 172
- End Page
- 178
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/190867
- DOI
- 10.1016/j.snb.2018.12.135
- ISSN
- 0925-4005
- Abstract
- We developed a novel optical sensor for sensitive and selective detection of catecholamines based on upconversion nanoparticles (UCNPs) decorated with different metal ions (UCNP-Men+). 1,2-ethanedithiol was chosen as a surface additive to synthesize the NaLuGdF4:Yb3+/Er3+ UCNPs by one-step at 200 degrees C. The as-prepared UCNPs exhibited a strong emission under the continuous excitation at 980 nm. It was found that catecholamines could be more effectively detected in the presence of UCNP-Fe3+, whereas, dopamine and epinephrine were detected selectively using UCNP-Li+ and UCNP-Cu2+ sensors, respectively. Under the optimum conditions, the limit of detections (LODs) for catecholamines, dopamine, and epinephrine are 2.8, 2.5, and 2.4 nM, respectively, with good linearity in the range of 5-320 nM for total catecholamines and 5-30 nM for dopamine and epinephrine. The developed method has been successfully applied to detect dopamine and epinephrine in human urine samples with good accuracy and satisfactory recovery.
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