Associations of serum calcium levels and dietary calcium intake with incident type 2 diabetes over 10 years: the Korean Genome and Epidemiology Study (KoGES)
DC Field | Value | Language |
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dc.contributor.author | Kim, Kyoung-Nam | - |
dc.contributor.author | Oh, Se-Young | - |
dc.contributor.author | Hong, Yun-Chul | - |
dc.date.accessioned | 2023-09-18T07:11:49Z | - |
dc.date.available | 2023-09-18T07:11:49Z | - |
dc.date.created | 2023-07-07 | - |
dc.date.issued | 2018-06 | - |
dc.identifier.issn | 1758-5996 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/190921 | - |
dc.description.abstract | Background: Previous evidence regarding the associations between serum calcium concentrations, dietary calcium intake, and type 2 diabetes (T2D) is limited. We investigated the longitudinal associations of serum calcium levels and dietary calcium intake with T2D development.,Methods: This study used data from the Ansung-Ansan cohort, a community-based, prospective cohort that was followed up for 10 years. Cox regression models adjusted for potential confounders were used to evaluate the associations of serum calcium levels (mean, 9.41 mg/dL) and dietary calcium intake (median, 389.59 mg/day) with T2D incidence. Association between dietary calcium intake and serum calcium levels was assessed using linear regression models.,Results: Albumin-adjusted serum calcium levels were not associated with T2D risk (hazard ratio [HR] = 1.07, 95% confidence interval [CI] 0.96, 1.19, p-value = 0.2333). A one-unit increase in log-transformed, energy-adjusted dietary calcium intake was associated with a decreased risk of T2D (HR = 0.88, 95% CI 0.77, 1.00, p-value = 0.0460) and lower albumin-adjusted serum calcium levels (beta = -0.04, 95% CI -0.07, -0.02, p-value = 0.0014). The associations did not differ according to sex (all p-values for interaction > 0.10).,Conclusions: Serum calcium levels were not associated with T2D risk, while higher dietary calcium intake was associated with a decreased risk of T2D development. These results have public health implications for predicting and preventing T2D development, as well as providing guidelines for diet and calcium supplementation. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | BMC | - |
dc.title | Associations of serum calcium levels and dietary calcium intake with incident type 2 diabetes over 10 years: the Korean Genome and Epidemiology Study (KoGES) | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Kyoung-Nam | - |
dc.identifier.doi | 10.1186/s13098-018-0349-y | - |
dc.identifier.scopusid | 2-s2.0-85048889998 | - |
dc.identifier.wosid | 000435610000001 | - |
dc.identifier.bibliographicCitation | DIABETOLOGY & METABOLIC SYNDROME, v.10, no.1, pp.1 - 7 | - |
dc.relation.isPartOf | DIABETOLOGY & METABOLIC SYNDROME | - |
dc.citation.title | DIABETOLOGY & METABOLIC SYNDROME | - |
dc.citation.volume | 10 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 7 | - |
dc.type.rims | ART | - |
dc.type.docType | 정기학술지(Article(Perspective Article포함)) | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Endocrinology & Metabolism | - |
dc.relation.journalWebOfScienceCategory | Endocrinology & Metabolism | - |
dc.subject.keywordPlus | CORONARY-HEART-DISEASE | - |
dc.subject.keywordPlus | VITAMIN-D | - |
dc.subject.keywordPlus | INSULIN-RESISTANCE | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | OBESITY | - |
dc.subject.keywordPlus | HEALTH | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | MAGNESIUM | - |
dc.subject.keywordPlus | GLUCOSE | - |
dc.subject.keywordPlus | ADULTS | - |
dc.subject.keywordAuthor | Cohort study | - |
dc.subject.keywordAuthor | Dietary calcium | - |
dc.subject.keywordAuthor | Serum calcium | - |
dc.subject.keywordAuthor | Type 2 diabetes mellitus | - |
dc.identifier.url | https://dmsjournal.biomedcentral.com/articles/10.1186/s13098-018-0349-y | - |
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