An approach to evaluate myocardial perfusion defect assessment for projection-based DECT: A phantom study
DC Field | Value | Language |
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dc.contributor.author | Han, Donghee | - |
dc.contributor.author | Shah, Sunny | - |
dc.contributor.author | Lee, Ji Hyun | - |
dc.contributor.author | Elmore, Kimberly | - |
dc.contributor.author | Gransar, Heidi | - |
dc.contributor.author | Danad, Ibrahim | - |
dc.contributor.author | Kumar, Vidhya | - |
dc.contributor.author | Raman, Subha | - |
dc.contributor.author | Hartaigh, Bríain Ó | - |
dc.contributor.author | Dunham, Simon | - |
dc.contributor.author | Lin, Fay Y | - |
dc.contributor.author | Min, James K. | - |
dc.date.accessioned | 2023-09-26T11:02:57Z | - |
dc.date.available | 2023-09-26T11:02:57Z | - |
dc.date.created | 2023-05-30 | - |
dc.date.issued | 2020-07 | - |
dc.identifier.issn | 0899-7071 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/191571 | - |
dc.description.abstract | Introduction: Dual-energy CT (DECT) can improve the accuracy of myocardial perfusion CT with projection-based monochromatic (DECT-MCE) and quantification of myocardial iodine in material decomposition (DECT-MD) reconstructions. However, evaluation of multiple reconstructions is laborious and the optimal reconstruction to detect myocardial perfusion defects is unknown. Methods: Left ventricular (LV) phantoms with artificial perfusion defects were scanned using DECT and single energy cardiac computed tomography angiography (SECT). Reconstructions of DECT-MCE at 40, 70, 100 and 140 keV, DECT-MD pairs of water, iodine, iron and fat, and SECT were evaluated using a 17-segment myocardial model. The diagnostic performance of each reconstruction was calculated on a per-segment basis and compared across DECT reconstructions. Results: Over 34 phantoms with artificial perfusion defects were found in 64/578 (11%) of segments, the sensitivity of DECT-MCE at 40, 70, 100, and 140 keV was 100% (95% confidence interval (CI): 93–100), 100% (95% CI: 93–100), 71% (95% CI: 56–83), and 25% (95% CI: 14–40), respectively, with a significant decline between 70 keV and 100 keV (p < 0.001). The specificity of DECT-MCE was 100% at all energies (95% CI: 99–100). As a group, the DECT-MD iodine background reconstructions had significantly lower sensitivity than the remaining modes (2.1% [95% CI, 0.05–11.1], vs. 100% [95% CI, 92.6–100], p < 0.001). Specificity of all material pair modes remained 100%. Conclusions: Using LV phantom models, the approach with the best sensitivity and specificity to assess myocardial perfusion defects with DECT are reconstructions of DECT-MCE at 40 or 70 KeV and DECT-MD without iodine background. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.title | An approach to evaluate myocardial perfusion defect assessment for projection-based DECT: A phantom study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Ji Hyun | - |
dc.identifier.doi | 10.1016/j.clinimag.2019.09.016 | - |
dc.identifier.scopusid | 2-s2.0-85080069102 | - |
dc.identifier.wosid | 000531059800003 | - |
dc.identifier.bibliographicCitation | CLINICAL IMAGING, pp.10 - 15 | - |
dc.relation.isPartOf | CLINICAL IMAGING | - |
dc.citation.title | CLINICAL IMAGING | - |
dc.citation.startPage | 10 | - |
dc.citation.endPage | 15 | - |
dc.type.rims | ART | - |
dc.type.docType | 정기학술지(Article(Perspective Article포함)) | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.subject.keywordPlus | DUAL-ENERGY CT | - |
dc.subject.keywordPlus | CORONARY-ARTERY STENOSIS | - |
dc.subject.keywordPlus | COMPUTED-TOMOGRAPHY ANGIOGRAPHY | - |
dc.subject.keywordPlus | DIAGNOSTIC PERFORMANCE | - |
dc.subject.keywordPlus | STRESS | - |
dc.subject.keywordPlus | HEART | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | SINGLE | - |
dc.subject.keywordAuthor | Computed tomography | - |
dc.subject.keywordAuthor | Dual energy | - |
dc.subject.keywordAuthor | Material decomposition | - |
dc.subject.keywordAuthor | Monochromatic | - |
dc.subject.keywordAuthor | Myocardial perfusion imaging | - |
dc.subject.keywordAuthor | Phantom | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0899707119302566?via%3Dihub | - |
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