A diaminotriazine-functionalized polydiacetylene for colorimetric sensing of thymine and oligothymidine
DC Field | Value | Language |
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dc.contributor.author | Jannah, Fadilatul | - |
dc.contributor.author | Heo, Jung-Moo | - |
dc.contributor.author | Park, Jaeyoung | - |
dc.contributor.author | Kim, Jong-Man | - |
dc.date.accessioned | 2023-11-24T05:21:56Z | - |
dc.date.available | 2023-11-24T05:21:56Z | - |
dc.date.created | 2023-05-22 | - |
dc.date.issued | 2023-09 | - |
dc.identifier.issn | 0925-4005 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/193116 | - |
dc.description.abstract | The development of analytical methods for qualitative and quantitative detection of DNA and its core bases has attracted great attention. In this study, a diaminotriazine (DAT)-containing polydiacetylene (PDA-DAT) colorimetric sensor was developed for selective detection of thymine and oligothymidine. PDA-DAT displayed a blue-to-purple color change in the presence of thymine with a detection limit of 12.6 nM. FTIR analysis demonstrated that the color change is associated with formation of multiple hydrogen bonds between the DAT and thymine moieties in a molecular recognition process. As a consequence of the hydrogen bonding interactions, a change in the conformation of the PDA conjugated backbone takes place, causing an absorption spectral shift and corresponding color change. The PDA-DAT sensor system also selectively detects oligothymidine (40 mer) with a detection limit of 14.6 nM. The results of this study should serve as a foundation for the design of colorimetric sensors for thymine and oligothymidine. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Elsevier B.V. | - |
dc.title | A diaminotriazine-functionalized polydiacetylene for colorimetric sensing of thymine and oligothymidine | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Jong-Man | - |
dc.identifier.doi | 10.1016/j.snb.2023.133871 | - |
dc.identifier.scopusid | 2-s2.0-85158051310 | - |
dc.identifier.wosid | 001052850300001 | - |
dc.identifier.bibliographicCitation | Sensors and Actuators B: Chemical, v.390, pp.1 - 8 | - |
dc.relation.isPartOf | Sensors and Actuators B: Chemical | - |
dc.citation.title | Sensors and Actuators B: Chemical | - |
dc.citation.volume | 390 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 8 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Electrochemistry | - |
dc.relation.journalResearchArea | Instruments & Instrumentation | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.relation.journalWebOfScienceCategory | Electrochemistry | - |
dc.relation.journalWebOfScienceCategory | Instruments & Instrumentation | - |
dc.subject.keywordPlus | SENSORS | - |
dc.subject.keywordPlus | GUANINE | - |
dc.subject.keywordPlus | ADENINE | - |
dc.subject.keywordPlus | DNA | - |
dc.subject.keywordAuthor | Polydiacetylene sensor | - |
dc.subject.keywordAuthor | Thymine | - |
dc.subject.keywordAuthor | Colorimetric | - |
dc.subject.keywordAuthor | Hydrogen bonding | - |
dc.subject.keywordAuthor | Diaminotriazine | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0925400523005865?via%3Dihub | - |
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