Association of Dipstick Proteinuria with Long-Term Mortality among Patients with Hypertensive Crisis in the Emergency Department
DC Field | Value | Language |
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dc.contributor.author | Kim, Byung Sik | - |
dc.contributor.author | Yu, Mi-Yeon | - |
dc.contributor.author | Park, Jin-Kyu | - |
dc.contributor.author | Shin, Jinho | - |
dc.contributor.author | Shin, Jeong-Hun | - |
dc.date.accessioned | 2024-01-10T01:00:23Z | - |
dc.date.available | 2024-01-10T01:00:23Z | - |
dc.date.issued | 2022-06 | - |
dc.identifier.issn | 2075-4426 | - |
dc.identifier.issn | 2075-4426 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/193812 | - |
dc.description.abstract | Proteinuria, frequently observed in hypertensive crisis, is a risk factor for cardiovascular and all-cause mortality in patients with hypertension. Here we investigated the association between proteinuria and all-cause mortality in patients with a hypertensive crisis in the emergency department (ED). This retrospective study included patients admitted to the ED of a tertiary referral center between 2016 and 2019 with hypertensive crisis (systolic blood pressure >= 180 mmHg or diastolic blood pressure >= 110 mmHg); 3599 patients with an assay for proteinuria were included in this study. Proteinuria was defined as a trace or more protein on a urine dipstick test. Proteinuria was present in 1964 (54.6%) of 3599 patients. At 3 years, crude all-cause mortality rates were 10.8% for patients with negative proteinuria, 21.7% for those with trace proteinuria, 29.0% for those with proteinuria (1+), 32.0% for those with proteinuria (2+), and 35.4% for those with proteinuria (>= 3+). After adjusting for age, sex, blood pressure, and comorbid conditions, the hazard ratio (95% confidence interval) for dipstick proteinuria was 1.91 (1.53-2.37) for those with trace proteinuria, 2.32 (1.85-2.91) for those with proteinuria (1+), 2.40 (1.86-3.10) for those with proteinuria (2+), and 2.40 (1.78-3.24) for those with proteinuria (>= 3+) compared to the reference of negative proteinuria. In patients with hypertensive crisis, dipstick proteinuria was a significant predictor of all-cause mortality, and the risk of all-cause mortality increased in a dose-dependent manner according to its degree. Moreover, even trace proteinuria was associated with an increased risk of mortality. The dipstick urine test could be used as a simple and useful method for risk assessment of all-cause mortality in patients with hypertensive crisis. | - |
dc.format.extent | 11 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | MDPI | - |
dc.title | Association of Dipstick Proteinuria with Long-Term Mortality among Patients with Hypertensive Crisis in the Emergency Department | - |
dc.type | Article | - |
dc.publisher.location | 스위스 | - |
dc.identifier.doi | 10.3390/jpm12060971 | - |
dc.identifier.scopusid | 2-s2.0-85132566685 | - |
dc.identifier.wosid | 000816556500001 | - |
dc.identifier.bibliographicCitation | JOURNAL OF PERSONALIZED MEDICINE, v.12, no.6, pp 1 - 11 | - |
dc.citation.title | JOURNAL OF PERSONALIZED MEDICINE | - |
dc.citation.volume | 12 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 11 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Health Care Sciences & Services | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Health Care Sciences & Services | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | CARDIOVASCULAR MORTALITY | - |
dc.subject.keywordPlus | AMERICAN-COLLEGE | - |
dc.subject.keywordPlus | ALL-CAUSE | - |
dc.subject.keywordPlus | MICROALBUMINURIA | - |
dc.subject.keywordPlus | POPULATION | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | ALBUMINURIA | - |
dc.subject.keywordPlus | PREVENTION | - |
dc.subject.keywordPlus | PREDICTION | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordAuthor | proteinuria | - |
dc.subject.keywordAuthor | hypertensive crisis | - |
dc.subject.keywordAuthor | emergency department | - |
dc.subject.keywordAuthor | mortality | - |
dc.identifier.url | https://www.mdpi.com/2075-4426/12/6/971 | - |
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