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Deciphering the molecular landscape of the FAM72 gene family: Implications for stem cell biology and cancer

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dc.contributor.authorRamesh, Janani-
dc.contributor.authorGopalakrishnan, Raja Mohan-
dc.contributor.authorNguyen, Tuan Hoang Anh-
dc.contributor.authorLai, Soak-Kuan-
dc.contributor.authorLi, Hoi-Yeung-
dc.contributor.authorKim, Pok-Son-
dc.contributor.authorKutzner, Arne-
dc.contributor.authorInoue, Noriko-
dc.contributor.authorHeese, Klaus-
dc.date.accessioned2026-04-07T00:00:19Z-
dc.date.available2026-04-07T00:00:19Z-
dc.date.issued2024-11-
dc.identifier.issn0197-0186-
dc.identifier.issn1872-9754-
dc.identifier.urihttps://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/212019-
dc.description.abstractFamily with sequence similarity 72 (FAM72) is a protein-coding gene family located on chromosome 1 in humans, uniquely featuring four paralogs: FAM72A, FAM72B, FAM72C, and FAM72D. While FAM72's presence as a gene pair with the SLIT-ROBO Rho GTPase-activating protein 2 (SRGAP2) is intriguing, its functional roles, particularly in neural stem cells, remain incompletely understood. This review explores the distinct characteristics of FAM72, shedding light on its expression patterns, potential roles in cell cycle regulation, stem cell renewal and implications in neurogenesis and tumorigenesis.-
dc.format.extent13-
dc.language영어-
dc.language.isoENG-
dc.publisherElsevier Ltd-
dc.titleDeciphering the molecular landscape of the FAM72 gene family: Implications for stem cell biology and cancer-
dc.typeArticle-
dc.publisher.location영국-
dc.identifier.doi10.1016/j.neuint.2024.105853-
dc.identifier.scopusid2-s2.0-85203159275-
dc.identifier.wosid001312773400001-
dc.identifier.bibliographicCitationNeurochemistry International, v.180, pp 1 - 13-
dc.citation.titleNeurochemistry International-
dc.citation.volume180-
dc.citation.startPage1-
dc.citation.endPage13-
dc.type.docTypeArticle-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaBiochemistry & Molecular Biology-
dc.relation.journalResearchAreaNeurosciences & Neurology-
dc.relation.journalWebOfScienceCategoryBiochemistry & Molecular Biology-
dc.relation.journalWebOfScienceCategoryNeurosciences-
dc.subject.keywordPlusURACIL-DNA GLYCOSYLASE-
dc.subject.keywordPlusBASE EXCISION-REPAIR-
dc.subject.keywordPlusPROTEIN-
dc.subject.keywordPlusFOXM1-
dc.subject.keywordPlusBRAIN-
dc.subject.keywordPlusTRANSCRIPTION-
dc.subject.keywordPlusORGANIZATION-
dc.subject.keywordPlusEVOLUTION-
dc.subject.keywordPlusPATHWAYS-
dc.subject.keywordPlusNUCLEAR-
dc.subject.keywordAuthorCell cycle-
dc.subject.keywordAuthorDNA repair-
dc.subject.keywordAuthorFOXM1-
dc.subject.keywordAuthorGlioblastoma-
dc.subject.keywordAuthorProliferation-
dc.subject.keywordAuthorStem cell-
dc.subject.keywordAuthorUNG-
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0197018624001803?via%3Dihub-
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