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Effectiveness of single-pill combination olmesartan/amlodipine/hydrochlorothiazide therapy in patients with apparent resistant hypertension

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dc.contributor.authorOh, Jaewon-
dc.contributor.authorKim, Wonho-
dc.contributor.authorKim, Gee-Hee-
dc.contributor.authorKim, Hack-Lyoung-
dc.contributor.authorPark, Sang-Don-
dc.contributor.authorMin, Kyung Wan-
dc.contributor.authorHyun, Dongkeun-
dc.contributor.authorHong, Jun Hwa-
dc.contributor.authorLim, Soo-
dc.contributor.authorBae, Ji-Hwan-
dc.contributor.authorShin, Jinho-
dc.date.accessioned2026-05-11T00:00:08Z-
dc.date.available2026-05-11T00:00:08Z-
dc.date.issued2025-09-
dc.identifier.issn0950-9240-
dc.identifier.issn1476-5527-
dc.identifier.urihttps://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/212606-
dc.description.abstractThis pioneering study investigated the real-life effectiveness of single-pill combination (SPC) antihypertensive therapy in patients with uncontrolled blood pressure (BP) and cardiovascular risk factors. After treatment with olmesartan medoxomil/amlodipine besylate/hydrochlorothiazide for 24 weeks, adults with apparent resistant hypertension had significantly reduced systolic BP and approximately 80% achieved target BP. SPC therapy may improve adherence in patients with pseudo-resistant hypertension and is a potentially effective treatment for resistant hypertension.-
dc.format.extent4-
dc.language영어-
dc.language.isoENG-
dc.publisherSPRINGERNATURE-
dc.titleEffectiveness of single-pill combination olmesartan/amlodipine/hydrochlorothiazide therapy in patients with apparent resistant hypertension-
dc.typeArticle-
dc.publisher.location영국-
dc.identifier.doi10.1038/s41371-025-01043-3-
dc.identifier.scopusid2-s2.0-105015807235-
dc.identifier.wosid001528208900001-
dc.identifier.bibliographicCitationJOURNAL OF HUMAN HYPERTENSION, v.39, no.9, pp 675 - 678-
dc.citation.titleJOURNAL OF HUMAN HYPERTENSION-
dc.citation.volume39-
dc.citation.number9-
dc.citation.startPage675-
dc.citation.endPage678-
dc.type.docTypeArticle-
dc.description.isOpenAccessY-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaCardiovascular System & Cardiology-
dc.relation.journalWebOfScienceCategoryPeripheral Vascular Disease-
dc.subject.keywordAuthorAmlodipine-
dc.subject.keywordAuthorHydrochlorothiazide-
dc.subject.keywordAuthorOlmesartan-
dc.subject.keywordAuthorAmlodipine-
dc.subject.keywordAuthorAntihypertensive Agents-
dc.subject.keywordAuthorDrug Combinations-
dc.subject.keywordAuthorHydrochlorothiazide-
dc.subject.keywordAuthorImidazoles-
dc.subject.keywordAuthorOlmesartan-
dc.subject.keywordAuthorOlmesartan Medoxomil-
dc.subject.keywordAuthorTetrazoles-
dc.subject.keywordAuthorAmlodipine-
dc.subject.keywordAuthorAntihypertensive Agent-
dc.subject.keywordAuthorHydrochlorothiazide-
dc.subject.keywordAuthorImidazole Derivative-
dc.subject.keywordAuthorOlmesartan-
dc.subject.keywordAuthorTetrazole Derivative-
dc.subject.keywordAuthorAdult-
dc.subject.keywordAuthorAged-
dc.subject.keywordAuthorBlood Pressure-
dc.subject.keywordAuthorCombination Drug Therapy-
dc.subject.keywordAuthorDiagnosis-
dc.subject.keywordAuthorDrug Combination-
dc.subject.keywordAuthorDrug Effect-
dc.subject.keywordAuthorDrug Resistance-
dc.subject.keywordAuthorDrug Therapy-
dc.subject.keywordAuthorFemale-
dc.subject.keywordAuthorHuman-
dc.subject.keywordAuthorHypertension-
dc.subject.keywordAuthorMale-
dc.subject.keywordAuthorMiddle Aged-
dc.subject.keywordAuthorPathophysiology-
dc.subject.keywordAuthorTreatment Outcome-
dc.subject.keywordAuthorAdult-
dc.subject.keywordAuthorAged-
dc.subject.keywordAuthorAmlodipine-
dc.subject.keywordAuthorAntihypertensive Agents-
dc.subject.keywordAuthorBlood Pressure-
dc.subject.keywordAuthorDrug Combinations-
dc.subject.keywordAuthorDrug Resistance-
dc.subject.keywordAuthorDrug Therapy, Combination-
dc.subject.keywordAuthorFemale-
dc.subject.keywordAuthorHumans-
dc.subject.keywordAuthorHydrochlorothiazide-
dc.subject.keywordAuthorHypertension-
dc.subject.keywordAuthorImidazoles-
dc.subject.keywordAuthorMale-
dc.subject.keywordAuthorMiddle Aged-
dc.subject.keywordAuthorOlmesartan Medoxomil-
dc.subject.keywordAuthorTetrazoles-
dc.subject.keywordAuthorTreatment Outcome-
dc.identifier.urlhttps://www.nature.com/articles/s41371-025-01043-3-
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