Is there a J-shaped relationship between the fatty liver index and risk of microalbuminuria in the general population?
DC Field | Value | Language |
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dc.contributor.author | Choi, Jong Wook | - |
dc.contributor.author | Oh, Il Hwan | - |
dc.contributor.author | Lee, Chang Hwa | - |
dc.contributor.author | Park, Joon-Sung | - |
dc.date.accessioned | 2021-07-30T04:56:38Z | - |
dc.date.available | 2021-07-30T04:56:38Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2018-06 | - |
dc.identifier.issn | 0009-8981 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/2357 | - |
dc.description.abstract | Background: We investigated whether the fatty liver index (FLI), as a clinical indicator of hepatic fat accumulation based on body mass index, gamma-glutamyl-transferase, triglycerides, and waist circumference, has an association with microalbuminuria. Methods: We analyzed anthropometric and biochemical data from a nation-wide, population-based, cross-sectional study. A total of 1605 participants included were healthy native Korean 40 years or older and divided into quintiles according to their log-FLI and sex. Microalbuminuria was defined as urine albumin/creatinine ratio (UACR) between 30 and 300 mg/g. Results: Participants in higher quintiles of log-FLI were more obese and hypertensive and had greater glycemic exposure, poorer lipid profiles, and greater increases in log-UACR compared with lower quintiles. Linear regression analysis demonstrated that log-FLI was associated with systolic and diastolic blood pressure, body mass index, waist circumference, fasting plasma glucose, glycated hemoglobin, and log-UACR. In logistic regression adjusted for age, sex, body mass index, waist circumference, and fasting plasma glucose, the OR of microalbuminuria was elevated in quintile 1 (adjusted OR = 2.161, 95% CI = 0.453-10.31) and quintile 5 (adjusted OR = 6.387, 95% CI = 1.317-51.58), when compared to quintile 2. Conclusions: There appears to be a J-shaped association between FLI and UACR in healthy general population. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.title | Is there a J-shaped relationship between the fatty liver index and risk of microalbuminuria in the general population? | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Chang Hwa | - |
dc.contributor.affiliatedAuthor | Park, Joon-Sung | - |
dc.identifier.doi | 10.1016/j.cca.2017.08.015 | - |
dc.identifier.scopusid | 2-s2.0-85029684750 | - |
dc.identifier.wosid | 000431936800037 | - |
dc.identifier.bibliographicCitation | CLINICA CHIMICA ACTA, v.481, pp.231 - 237 | - |
dc.relation.isPartOf | CLINICA CHIMICA ACTA | - |
dc.citation.title | CLINICA CHIMICA ACTA | - |
dc.citation.volume | 481 | - |
dc.citation.startPage | 231 | - |
dc.citation.endPage | 237 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Medical Laboratory Technology | - |
dc.relation.journalWebOfScienceCategory | Medical Laboratory Technology | - |
dc.subject.keywordPlus | CHRONIC KIDNEY-DISEASE | - |
dc.subject.keywordPlus | BODY-MASS INDEX | - |
dc.subject.keywordPlus | METABOLIC SYNDROME | - |
dc.subject.keywordPlus | SYSTEMIC INFLAMMATION | - |
dc.subject.keywordPlus | WAIST CIRCUMFERENCE | - |
dc.subject.keywordPlus | RENAL-FAILURE | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | NAFLD | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordPlus | ATHEROSCLEROSIS | - |
dc.subject.keywordAuthor | Fatty liver index | - |
dc.subject.keywordAuthor | Metabolic syndrome | - |
dc.subject.keywordAuthor | Microalbuminuria | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S000989811730308X?via%3Dihub | - |
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