Memory loss and decreased executive function are associated with limited functional capacity in patients with heart failure compared to patients with other medical conditions
- Authors
- Kim, JinShil; Shin, Mi-Seung; Hwang, Seon Young; Park, Eunok; Lim, Young-Hyo; Shim, Jae Lan; Kim, Sun Liwa; Kim, Yeon Hee; An, Minjeong
- Issue Date
- Jan-2018
- Publisher
- MOSBY-ELSEVIER
- Keywords
- Cognitive function; Heart failure; Medical conditions; Functional capacity
- Citation
- HEART & LUNG, v.47, no.1, pp.61 - 67
- Indexed
- SCIE
SCOPUS
- Journal Title
- HEART & LUNG
- Volume
- 47
- Number
- 1
- Start Page
- 61
- End Page
- 67
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/2444
- DOI
- 10.1016/j.hrtlng.2017.09.005
- ISSN
- 0147-9563
- Abstract
- Background
There is limited evidence on the degree of cognitive impairment and its association with physical functional capacity among patients with heart failure (HF) in Korea.
Objectives
In this study, we compared cognitive impairment between patients with HF and community-dwelling participants with non-HF medical conditions (medical participants) and its association with physical functional capacity.
Methods
We conducted a cross-sectional comparative study and assessed the neuropsychological cognitive status (Seoul Neuropsychological Screening Battery) and physical functional capacity (Duke Activity Status Index) of patients with HF and medical participants using face-to-face interviews.
Results
One hundred and eighteen patients with HF (age, 65.45 ± 9.38 years; men, 57.6%; left ventricular ejection fraction, 34.93 ± 8.72%) and 83 medical participants (age, 66.02 ± 8.28 years; men, 47.0%) were included. Using seventh-percentile medical participant Z-scores as cutoffs, memory and executive function were worse in patients with HF than in medical participants: immediate (35.0% vs. 6.0%) and delayed recall memory (34.5% vs. 8.4%), and executive function (28.6% vs. 6.0%). Independent of age, sex, education, comorbidity, and HF status, executive function was a significant predictor of physical functional capacity (b = 1.82, p = .021).
Conclusions
More patients with HF had impaired memory and executive function, which were associated with their physical functional capacities.
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