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Cited 9 time in webofscience Cited 9 time in scopus
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A novel peptide-based recognition probe for the sensitive detection of CD44 on breast cancer stem cells

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dc.contributor.authorCho, Jun-Haeng-
dc.contributor.authorLee, Sang-Choon-
dc.contributor.authorHa, Na-Reum-
dc.contributor.authorLee, Su-Jae-
dc.contributor.authorYoon, Moon-Young-
dc.date.accessioned2021-08-02T17:52:24Z-
dc.date.available2021-08-02T17:52:24Z-
dc.date.issued2015-12-
dc.identifier.issn0890-8508-
dc.identifier.issn1096-1194-
dc.identifier.urihttps://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/24778-
dc.description.abstractMetastasis and recurrence of breast cancer remain significant clinical problems. The expression level of CD44 protein is higher in breast cancer-initiating cancer stem cells; therefore, the early detection of CD44 using a sensitive diagnostic probe is important for breast cancer diagnosis and therapeutic purposes. In this study, we fabricated a polyvalent directed peptide polymer (PDPP) that specifically recognized the CD44 biomarker, as confirmed by immunocytochemistry tests and fluorescence-activated cell sorting assessment. Our results indicate that PDPP is useful as a novel tool for the sensitive detection of breast cancer stem cells. (C) 2015 Elsevier Ltd. All rights reserved.-
dc.format.extent8-
dc.language영어-
dc.language.isoENG-
dc.publisherAcademic Press-
dc.titleA novel peptide-based recognition probe for the sensitive detection of CD44 on breast cancer stem cells-
dc.typeArticle-
dc.publisher.location영국-
dc.identifier.doi10.1016/j.mcp.2015.05.014-
dc.identifier.scopusid2-s2.0-84951573422-
dc.identifier.wosid000367211900023-
dc.identifier.bibliographicCitationMolecular and Cellular Probes, v.29, no.6, pp 492 - 499-
dc.citation.titleMolecular and Cellular Probes-
dc.citation.volume29-
dc.citation.number6-
dc.citation.startPage492-
dc.citation.endPage499-
dc.type.docTypeArticle-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClasssci-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaBiochemistry & Molecular Biology-
dc.relation.journalResearchAreaBiotechnology & Applied Microbiology-
dc.relation.journalResearchAreaCell Biology-
dc.relation.journalWebOfScienceCategoryBiochemical Research Methods-
dc.relation.journalWebOfScienceCategoryBiochemistry & Molecular Biology-
dc.relation.journalWebOfScienceCategoryBiotechnology & Applied Microbiology-
dc.relation.journalWebOfScienceCategoryCell Biology-
dc.subject.keywordPlusHYALURONAN-
dc.subject.keywordPlusMACROMOLECULES-
dc.subject.keywordPlusRESISTANCE-
dc.subject.keywordPlusTARGETS-
dc.subject.keywordPlusBRAIN-
dc.subject.keywordAuthorCD44-
dc.subject.keywordAuthorBreast cancer stem cell-
dc.subject.keywordAuthorPeptide-
dc.subject.keywordAuthorPDPP-
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