Changes in Quality of Life in the First 5 Years of Disease in a Multicenter Cohort of Patients With Systemic Lupus Erythematosus
DC Field | Value | Language |
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dc.contributor.author | Urowitz, M. | - |
dc.contributor.author | Gladman, D. D. | - |
dc.contributor.author | Ibanez, D. | - |
dc.contributor.author | Sanchez-Guerrero, J. | - |
dc.contributor.author | Bae, Sang Cheol | - |
dc.contributor.author | Gordon, C. | - |
dc.contributor.author | Fortin, P. R. | - |
dc.contributor.author | Clarke, A. | - |
dc.contributor.author | Bernatsky, S. | - |
dc.contributor.author | Hanly, J. G. | - |
dc.date.accessioned | 2021-08-02T18:29:19Z | - |
dc.date.available | 2021-08-02T18:29:19Z | - |
dc.date.created | 2021-05-13 | - |
dc.date.issued | 2014-09 | - |
dc.identifier.issn | 2151-464X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/25773 | - |
dc.description.abstract | Objective. The Medical Outcomes Study Short Form 36 (SF-36) is recommended to assess quality of life (QOL) in systemic lupus erythematosus (SLE). The aim of the current study was to assess QOL over time in the first 5 years of a multicenter inception cohort of patients with SLE. Methods. An inception SLE cohort was assembled according to a standardized protocol between 2000 and 2012. In addition to clinical and laboratory assessments, patients completed the SF-36 at yearly intervals. Only patients who had ˃= 5 completed QOL questionnaires were included in these analyses. Generalized estimating equation models were run separately for each of the 8 subscales and for the physical and mental component summary scores, adjusting for repeated measures by patients. Results. A total of 495 patients were included. The mean +/- SD disease duration at the first visit was 5.3 +/- 4.1 months. The mean +/- SD age at enrollment was 35.8 +/- 13.2 years. All 8 subscales and the 2 summary scores showed improvement in the first 2 years from enrollment. Between years 2 and 5, none of the subscales or summary scores showed any change. Minimum clinically important improvement was achieved by 35-56% of the patients and was influenced by demographic and disease factors. Conclusion. Unlike late-stage lupus, where QOL is stable over time, in patients with early disease, all subscales improve in early followup up to 2 years. Therefore, the SF-36 may be a sensitive outcome measure in early disease in patients with SLE. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | WILEY-BLACKWELL | - |
dc.title | Changes in Quality of Life in the First 5 Years of Disease in a Multicenter Cohort of Patients With Systemic Lupus Erythematosus | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Bae, Sang Cheol | - |
dc.identifier.doi | 10.1002/acr.22299 | - |
dc.identifier.scopusid | 2-s2.0-84906703030 | - |
dc.identifier.wosid | 000341241200013 | - |
dc.identifier.bibliographicCitation | ARTHRITIS CARE & RESEARCH, v.66, no.9, pp.1374 - 1379 | - |
dc.relation.isPartOf | ARTHRITIS CARE & RESEARCH | - |
dc.citation.title | ARTHRITIS CARE & RESEARCH | - |
dc.citation.volume | 66 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 1374 | - |
dc.citation.endPage | 1379 | - |
dc.type.rims | ART | - |
dc.type.docType | 정기학술지(Article(Perspective Article포함)) | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Rheumatology | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1002/acr.22299 | - |
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