Factors Influencing Discrepancies Between the QuantiFERON-TB Gold in Tube Test and the Tuberculin Skin Test in Korean Patients with Rheumatic Diseases
DC Field | Value | Language |
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dc.contributor.author | Kim, Jae-Hoon | - |
dc.contributor.author | Cho, Soo-Kyung | - |
dc.contributor.author | Han, Minkyung | - |
dc.contributor.author | Choi, Chan-Bum | - |
dc.contributor.author | Kim, Tae-Hwan | - |
dc.contributor.author | Jun, Jae-Bum | - |
dc.contributor.author | Bae, Sang-Cheol | - |
dc.contributor.author | Yoo, Dae-Hyun | - |
dc.contributor.author | Sung, Yoon-Kyoung | - |
dc.date.accessioned | 2021-08-02T18:58:07Z | - |
dc.date.available | 2021-08-02T18:58:07Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2013-02 | - |
dc.identifier.issn | 0049-0172 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/26785 | - |
dc.description.abstract | Objectives To estimate the positivity and agreement between QuantiFERON-tuberculosis (TB) gold in tube test (QFT-GIT) and tuberculin skin test (TST) according to underlying rheumatic diseases and to identify the influencing factors on discrepancies between the 2 tests. Methods Among the 757 patients who underwent both QFT-GIT and TST simultaneously from September 2008 to November 2010, patients with indeterminate QFT-GIT results (n = 21), with active (n = 11) or suspicious (n = 1) findings for tuberculosis on a chest radiograph, were excluded. Finally, 724 patients were recruited for this study: 497 patients with rheumatoid arthritis (RA), 198 with ankylosing spondylitis (AS), and 29 with juvenile rheumatoid arthritis (JRA). The agreement between the 2 tests was estimated by Cohen's κ and factors influencing discrepancies were identified using multivariate analysis. Results The positivity of QFT-GIT was higher in RA than AS or JRA (30.2%, 16.2%, and 3.4%, respectively). In contrast, TST positivity was highest in AS compared to RA and JRA (45.5%, 28.2%, and 17.2%, respectively). The agreement between the 2 tests was low in all patients (κ = 0.285). The only predictor of a discrepancy between the 2 tests was older age. Factors associated with discordant QFT-GIT-negative/TST-positive results were female [odds ratio (OR) = 2.33, confidence interval (CI) 1.11 to 4.89] and AS (OR = 3.12, CI 1.44 to 6.79), whereas a discordant QFT-GIT-positive/TST-negative result was associated with glucocorticoid use (OR = 2.44, CI 1.24 to 4.81). Conclusions The agreement between the 2 tests is low; therefore, it would be better to perform both tests than to use any 1 test alone for the detection of LTBI in TB-endemic regions. Female and underlying AS are related to being QFT-GIT-negative/TST-positive, and the use of glucocorticoid is associated with being QFT-GIT-positive/TST-negative. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | W B SAUNDERS CO-ELSEVIER INC | - |
dc.title | Factors Influencing Discrepancies Between the QuantiFERON-TB Gold in Tube Test and the Tuberculin Skin Test in Korean Patients with Rheumatic Diseases | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Cho, Soo-Kyung | - |
dc.contributor.affiliatedAuthor | Choi, Chan-Bum | - |
dc.contributor.affiliatedAuthor | Kim, Tae-Hwan | - |
dc.contributor.affiliatedAuthor | Jun, Jae-Bum | - |
dc.contributor.affiliatedAuthor | Bae, Sang-Cheol | - |
dc.contributor.affiliatedAuthor | Yoo, Dae-Hyun | - |
dc.contributor.affiliatedAuthor | Sung, Yoon-Kyoung | - |
dc.identifier.doi | 10.1016/j.semarthrit.2012.07.001 | - |
dc.identifier.scopusid | 2-s2.0-84873736775 | - |
dc.identifier.wosid | 000315748500011 | - |
dc.identifier.bibliographicCitation | SEMINARS IN ARTHRITIS AND RHEUMATISM, v.42, no.4, pp.424 - 432 | - |
dc.relation.isPartOf | SEMINARS IN ARTHRITIS AND RHEUMATISM | - |
dc.citation.title | SEMINARS IN ARTHRITIS AND RHEUMATISM | - |
dc.citation.volume | 42 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 424 | - |
dc.citation.endPage | 432 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Rheumatology | - |
dc.relation.journalWebOfScienceCategory | Rheumatology | - |
dc.subject.keywordPlus | TUMOR-NECROSIS-FACTOR | - |
dc.subject.keywordPlus | INTERFERON-GAMMA ASSAY | - |
dc.subject.keywordPlus | ANKYLOSING-SPONDYLITIS | - |
dc.subject.keywordPlus | FACTOR ANTAGONISTS | - |
dc.subject.keywordPlus | FACTOR BLOCKERS | - |
dc.subject.keywordPlus | RELEASE ASSAYS | - |
dc.subject.keywordPlus | INFECTION | - |
dc.subject.keywordPlus | ARTHRITIS | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | RECOMMENDATIONS | - |
dc.subject.keywordAuthor | QuantiFERON-TB gold in tube test | - |
dc.subject.keywordAuthor | tuberculin skin test | - |
dc.subject.keywordAuthor | latent tuberculosis infection | - |
dc.subject.keywordAuthor | tumor necrosis factor inhibitor | - |
dc.subject.keywordAuthor | rheumatic disease | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0049017212001710?via%3Dihub | - |
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