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Cited 6 time in webofscience Cited 6 time in scopus
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Phage Display Screen for Peptides That Bind Bcl-2 Protein

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dc.contributor.authorPark, Hye-Yeon-
dc.contributor.authorKim, Joungmok-
dc.contributor.authorCho, June-Haeng-
dc.contributor.authorMoon, Ji Young-
dc.contributor.authorLee, Su-Jae-
dc.contributor.authorYoon, Moon-Young-
dc.date.accessioned2021-08-02T19:53:20Z-
dc.date.available2021-08-02T19:53:20Z-
dc.date.issued2011-01-
dc.identifier.issn1552-454X-
dc.identifier.issn1552-454X-
dc.identifier.urihttps://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/28193-
dc.description.abstractBcl-2 family proteins are key regulators of apoptosis associated with human disease, including cancer. Bcl-2 protein has been found to be overexpressed in many cancer cells. Therefore, Bcl-2 protein is a potential diagnostic target for cancer detection. In the present study, the authors have identified several Bcl-2 binding peptides with high affinity (picomolar range) from a 5-round M13 phage display library screening. These peptides can be used to develop novel diagnostic probes or potent inhibitors with diverse polyvalencies. (Journal of Biomolecular Screening 2011:82-89)-
dc.format.extent8-
dc.language영어-
dc.language.isoENG-
dc.titlePhage Display Screen for Peptides That Bind Bcl-2 Protein-
dc.typeArticle-
dc.identifier.doi10.1177/1087057110385816-
dc.identifier.scopusid2-s2.0-78951485292-
dc.identifier.wosid000286063300009-
dc.identifier.bibliographicCitationJournal of biomolecular screening, v.16, no.1, pp 82 - 89-
dc.citation.titleJournal of biomolecular screening-
dc.citation.volume16-
dc.citation.number1-
dc.citation.startPage82-
dc.citation.endPage89-
dc.type.docTypeArticle-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaBiochemistry & Molecular Biology-
dc.relation.journalResearchAreaBiotechnology & Applied Microbiology-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalWebOfScienceCategoryBiochemical Research Methods-
dc.relation.journalWebOfScienceCategoryBiotechnology & Applied Microbiology-
dc.relation.journalWebOfScienceCategoryChemistry, Analytical-
dc.subject.keywordPlusCELL-DEATH-
dc.subject.keywordPlusFAMILY PROTEINS-
dc.subject.keywordPlusEPITOPE LIBRARY-
dc.subject.keywordPlusGENE FAMILY-
dc.subject.keywordPlusCANCER-
dc.subject.keywordPlusAPOPTOSIS-
dc.subject.keywordPlusIDENTIFICATION-
dc.subject.keywordPlusSURVIVAL-
dc.subject.keywordPlusTUMORIGENESIS-
dc.subject.keywordPlusSTRATEGIES-
dc.subject.keywordAuthorcancer-
dc.subject.keywordAuthorapoptosis-
dc.subject.keywordAuthordiagnostics probe-
dc.subject.keywordAuthorBcl-2 protein-binding peptides-
dc.subject.keywordAuthorM13 phage display-
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