Phage Display Screen for Peptides That Bind Bcl-2 Protein
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Hye-Yeon | - |
dc.contributor.author | Kim, Joungmok | - |
dc.contributor.author | Cho, June-Haeng | - |
dc.contributor.author | Moon, Ji Young | - |
dc.contributor.author | Lee, Su-Jae | - |
dc.contributor.author | Yoon, Moon-Young | - |
dc.date.accessioned | 2021-08-02T19:53:20Z | - |
dc.date.available | 2021-08-02T19:53:20Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2011-01 | - |
dc.identifier.issn | 1087-0571 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/28193 | - |
dc.description.abstract | Bcl-2 family proteins are key regulators of apoptosis associated with human disease, including cancer. Bcl-2 protein has been found to be overexpressed in many cancer cells. Therefore, Bcl-2 protein is a potential diagnostic target for cancer detection. In the present study, the authors have identified several Bcl-2 binding peptides with high affinity (picomolar range) from a 5-round M13 phage display library screening. These peptides can be used to develop novel diagnostic probes or potent inhibitors with diverse polyvalencies. (Journal of Biomolecular Screening 2011:82-89) | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | SAGE PUBLICATIONS INC | - |
dc.title | Phage Display Screen for Peptides That Bind Bcl-2 Protein | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Su-Jae | - |
dc.identifier.doi | 10.1177/1087057110385816 | - |
dc.identifier.scopusid | 2-s2.0-78951485292 | - |
dc.identifier.wosid | 000286063300009 | - |
dc.identifier.bibliographicCitation | JOURNAL OF BIOMOLECULAR SCREENING, v.16, no.1, pp.82 - 89 | - |
dc.relation.isPartOf | JOURNAL OF BIOMOLECULAR SCREENING | - |
dc.citation.title | JOURNAL OF BIOMOLECULAR SCREENING | - |
dc.citation.volume | 16 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 82 | - |
dc.citation.endPage | 89 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Biochemical Research Methods | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.subject.keywordPlus | CELL-DEATH | - |
dc.subject.keywordPlus | FAMILY PROTEINS | - |
dc.subject.keywordPlus | EPITOPE LIBRARY | - |
dc.subject.keywordPlus | GENE FAMILY | - |
dc.subject.keywordPlus | CANCER | - |
dc.subject.keywordPlus | APOPTOSIS | - |
dc.subject.keywordPlus | IDENTIFICATION | - |
dc.subject.keywordPlus | SURVIVAL | - |
dc.subject.keywordPlus | TUMORIGENESIS | - |
dc.subject.keywordPlus | STRATEGIES | - |
dc.subject.keywordAuthor | cancer | - |
dc.subject.keywordAuthor | apoptosis | - |
dc.subject.keywordAuthor | diagnostics probe | - |
dc.subject.keywordAuthor | Bcl-2 protein-binding peptides | - |
dc.subject.keywordAuthor | M13 phage display | - |
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