A novel approach for amine derivatization of MoS2 nanosheets and their application toward label-free immunosensor
DC Field | Value | Language |
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dc.contributor.author | Kukkar, Manil | - |
dc.contributor.author | Tuteja, Satish K. | - |
dc.contributor.author | Kumar, Parveen | - |
dc.contributor.author | Kim, Ki-Hyun | - |
dc.contributor.author | Bhadwal, Akhshay Singh | - |
dc.contributor.author | Deep, Akash | - |
dc.date.accessioned | 2021-07-30T05:07:01Z | - |
dc.date.available | 2021-07-30T05:07:01Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2018-08 | - |
dc.identifier.issn | 0003-2697 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/3069 | - |
dc.description.abstract | The application of molybdenum disulfide (MoS2) nanosheets has assumed great significance in the design of next-generation biosensors. The immobilization of biomolecules on MoS2 nanosheets has generally been achieved via hydrophobic interactions or through other complicated surface modifications. In this work, we report a novel strategy for electrochemically assisted amine derivatization of MoS2 nanosheets. This newly proposed approach helped to immobilize the MoS2 nanosheets with antibodies via facile EDC/NHS {N-(3-dimethylaminopropy1)-N-(ethylcarbodiimide/N-hydroxysuccinimide)} cross-linking chemistry. The MoS2 nanosheets were first exfoliated and then electrochemically modified with 2-aminobenzylamine. Through a subsequent bioconjugation of the above amine-derivatized MoS2 nanosheets with anti-prostate-specific antigen (PSA) antibodies, an inununosensing device was realized for the detection of the 'prostate specific antigen'. The application of the proposed immunosensor was characterized with a low detection limit (10(-3) ng/mL) over a very wide quantitation range (10(-3) to 200 ng/mL). | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ACADEMIC PRESS INC ELSEVIER SCIENCE | - |
dc.title | A novel approach for amine derivatization of MoS2 nanosheets and their application toward label-free immunosensor | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Ki-Hyun | - |
dc.identifier.doi | 10.1016/j.ab.2018.05.029 | - |
dc.identifier.scopusid | 2-s2.0-85048165112 | - |
dc.identifier.wosid | 000440118200001 | - |
dc.identifier.bibliographicCitation | ANALYTICAL BIOCHEMISTRY, v.555, pp.1 - 8 | - |
dc.relation.isPartOf | ANALYTICAL BIOCHEMISTRY | - |
dc.citation.title | ANALYTICAL BIOCHEMISTRY | - |
dc.citation.volume | 555 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 8 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Biochemical Research Methods | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.subject.keywordPlus | HIGHLY SENSITIVE DETECTION | - |
dc.subject.keywordPlus | PROSTATE-SPECIFIC ANTIGEN | - |
dc.subject.keywordPlus | FREE ELECTROCHEMICAL IMMUNOSENSOR | - |
dc.subject.keywordPlus | FUNCTIONALIZED GRAPHENE | - |
dc.subject.keywordPlus | SIGNAL AMPLIFICATION | - |
dc.subject.keywordPlus | CANCER | - |
dc.subject.keywordPlus | TRANSITION | - |
dc.subject.keywordPlus | BIOSENSOR | - |
dc.subject.keywordPlus | NANOCOMPOSITES | - |
dc.subject.keywordPlus | NANOPARTICLES | - |
dc.subject.keywordAuthor | MoS2 | - |
dc.subject.keywordAuthor | Electrochemical derivatization | - |
dc.subject.keywordAuthor | Amine functionality | - |
dc.subject.keywordAuthor | EDC-NHS | - |
dc.subject.keywordAuthor | Prostate-specific antigen | - |
dc.subject.keywordAuthor | Immunosensor | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0003269718305414?via%3Dihub | - |
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