Clinical risk stratification model for advanced colorectal neoplasia in persons with negative fecal immunochemical test results
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jung, Yoon Suk | - |
dc.contributor.author | Park, Chan Hyuk | - |
dc.contributor.author | Kim, Nam Hee | - |
dc.contributor.author | Park, Jung Ho | - |
dc.contributor.author | Park, Dong Il | - |
dc.contributor.author | Sohn, Chong Il | - |
dc.date.accessioned | 2021-07-30T05:07:29Z | - |
dc.date.available | 2021-07-30T05:07:29Z | - |
dc.date.created | 2021-05-11 | - |
dc.date.issued | 2018-01 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/3182 | - |
dc.description.abstract | Objectives The fecal immunochemical test (FIT) has low sensitivity for detecting advanced colorectal neoplasia (ACRN); thus, a considerable portion of FIT-negative persons may have ACRN. We aimed to develop a risk-scoring model for predicting ACRN in FIT-negative persons. Materials and methods We reviewed the records of participants aged ≥40 years who underwent a colonoscopy and FIT during a health check-up. We developed a risk-scoring model for predicting ACRN in FIT-negative persons. Results Of 11,873 FIT-negative participants, 255 (2.1%) had ACRN. On the basis of the multivariable logistic regression model, point scores were assigned as follows among FIT-negative persons: age (per year from 40 years old), 1 point; current smoker, 10 points; overweight, 5 points; obese, 7 points; hypertension, 6 points; old cerebrovascular attack (CVA), 15 points. Although the proportion of ACRN in FIT-negative persons increased as risk scores increased (from 0.6% in the group with 0–4 points to 8.1% in the group with 35–39 points), it was significantly lower than that in FIT-positive persons (14.9%). However, there was no statistical difference between the proportion of ACRN in FIT-negative persons with ≥40 points and in FIT-positive persons (10.5% vs. 14.9%, P = 0.321). Conclusions FIT-negative persons may need to undergo screening colonoscopy if they clinically have a high risk of ACRN. The scoring model based on age, smoking habits, overweight or obesity, hypertension, and old CVA may be useful in selecting and prioritizing FIT-negative persons for screening colonoscopy. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | PUBLIC LIBRARY SCIENCE | - |
dc.title | Clinical risk stratification model for advanced colorectal neoplasia in persons with negative fecal immunochemical test results | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Park, Chan Hyuk | - |
dc.identifier.doi | 10.1371/journal.pone.0191125 | - |
dc.identifier.scopusid | 2-s2.0-85040371192 | - |
dc.identifier.wosid | 000419952400118 | - |
dc.identifier.bibliographicCitation | PLOS ONE, v.13, no.1 | - |
dc.relation.isPartOf | PLOS ONE | - |
dc.citation.title | PLOS ONE | - |
dc.citation.volume | 13 | - |
dc.citation.number | 1 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordPlus | CANCER INCIDENCE | - |
dc.subject.keywordPlus | COLONOSCOPY | - |
dc.subject.keywordPlus | ATHEROSCLEROSIS | - |
dc.subject.keywordPlus | SIGMOIDOSCOPY | - |
dc.subject.keywordPlus | POPULATION | - |
dc.subject.keywordPlus | INDEX | - |
dc.subject.keywordPlus | ASIA | - |
dc.identifier.url | https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0191125 | - |
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