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Treatment outcomes of macrolide-susceptible Mycobacterium abscessus lung disease
- Authors
- Choi H.; Jhun B.W.; Kim S.-Y.; Kim D.H.; Lee, Hyun; Jeon K.; Kwon O.J.; Huh H.J.; Ki C.-S.; Lee N.Y.; Shin S.J.; Daley C.L.; Koh W.-J.
- Issue Date
- Apr-2018
- Publisher
- ELSEVIER SCIENCE INC
- Keywords
- Nontuberculous mycobacteria; Mycobacterium abscessus; Macrolides; Drug resistance; Treatment
- Citation
- DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, v.90, no.4, pp.293 - 295
- Indexed
- SCIE
SCOPUS
- Journal Title
- DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
- Volume
- 90
- Number
- 4
- Start Page
- 293
- End Page
- 295
- ISSN
- 0732-8893
- Abstract
- Mycobacterium abscessus lung disease is difficult to treat due to inducible resistance to macrolides. However, 15%-20% of isolates are macrolide susceptible. In 14 patients with macrolide-susceptible M. abscessus lung disease, all isolates had nonfunctional erm(41) gene, and sputum culture conversion rate was achieved in 93% (13/14) following antibiotic therapy.
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