Estimating Negative Effect of Abdominal Obesity on Mildly Decreased Kidney Function Using a Novel Index of Body-Fat Distribution
DC Field | Value | Language |
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dc.contributor.author | Oh, Il Hwan | - |
dc.contributor.author | Choi, Jong Wook | - |
dc.contributor.author | Lee, Chang Hwa | - |
dc.contributor.author | Park, Joon-Sung | - |
dc.date.accessioned | 2021-07-30T05:12:18Z | - |
dc.date.available | 2021-07-30T05:12:18Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2017-04 | - |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/3557 | - |
dc.description.abstract | Abdominal obesity is a major risk factor of chronic kidney disease (CKD). Conventional obesity-related indicators, included body mass index (BMI), waist circumference (WC), and conicity index (C-index), have some limitations. We examined the usefulness of trunk/body fat mass ratio (T/Br) to predict negative effect of abnormal fat distribution on excretory kidney function. We analyzed anthropometric, biochemical and densitometric data from a nation-wide, population-based, case-control study (the Korean National Health and Nutrition Examination Survey [KNHANES] IV and V). A total of 11,319 participants were divided into 2 groups according to estimated glomerular filtration rate (eGFR, mL·min-1·1.73 m-2) as follows: Group I (n = 7,980), eGFR ≥ 90 and ≤ 120; and group II (n = 3,339), eGFR ≥ 60 and < 90. Linear regression analysis revealed that T/Br was closely related to eGFR (β = −0.3173, P < 0.001), and the correlation remained significant after adjustment for age, gender, BMI, WC, C-index, systolic blood pressure (BP), hemoglobin, and smoking amount (β = −0.0987, P < 0.001). Logistic regression analysis showed that T/Br (odds ratio [OR] = 1.046; 95% confidence interval [CI] = 1.039–1.054) was significantly associated with early decline of kidney function, and adjustment for age, gender, BMI, C-index, systolic BP, hemoglobin, serum glucose level, high-density lipoprotein (HDL)-cholesterol, and smoking amount did not reduce the association (OR = 1.020; 95% CI = 1.007–1.033). T/Br is useful in estimating the negative impact of abdominal obesity on the kidney function. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN ACAD MEDICAL SCIENCES | - |
dc.title | Estimating Negative Effect of Abdominal Obesity on Mildly Decreased Kidney Function Using a Novel Index of Body-Fat Distribution | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Chang Hwa | - |
dc.contributor.affiliatedAuthor | Park, Joon-Sung | - |
dc.identifier.doi | 10.3346/jkms.2017.32.4.613 | - |
dc.identifier.scopusid | 2-s2.0-85015176201 | - |
dc.identifier.wosid | 000402683100010 | - |
dc.identifier.bibliographicCitation | JOURNAL OF KOREAN MEDICAL SCIENCE, v.32, no.4, pp.613 - 620 | - |
dc.relation.isPartOf | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.citation.title | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.citation.volume | 32 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 613 | - |
dc.citation.endPage | 620 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002211210 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | GLOMERULAR-FILTRATION-RATE | - |
dc.subject.keywordPlus | CARDIOVASCULAR-DISEASE | - |
dc.subject.keywordPlus | WAIST CIRCUMFERENCE | - |
dc.subject.keywordPlus | METABOLIC SYNDROME | - |
dc.subject.keywordPlus | VISCERAL FAT | - |
dc.subject.keywordPlus | MASS INDEX | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | INFLAMMATION | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordAuthor | Abdominal Obesity | - |
dc.subject.keywordAuthor | Densitometry | - |
dc.subject.keywordAuthor | Trunk/Body Fat Mass Ratio | - |
dc.subject.keywordAuthor | Glomerular Filtration Rate | - |
dc.identifier.url | https://jkms.org/DOIx.php?id=10.3346/jkms.2017.32.4.613 | - |
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