MOF-Bacteriophage Biosensor for Highly Sensitive and Specific Detection of Staphylococcus aureus
DC Field | Value | Language |
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dc.contributor.author | Bhardwaj, Neha | - |
dc.contributor.author | Bhardwaj, Sanjeev K. | - |
dc.contributor.author | Mehta, Jyotsana | - |
dc.contributor.author | Kim, Ki-Hyun | - |
dc.contributor.author | Deep, Akash | - |
dc.date.accessioned | 2021-07-30T05:18:08Z | - |
dc.date.available | 2021-07-30T05:18:08Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2017-10 | - |
dc.identifier.issn | 1944-8244 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/4043 | - |
dc.description.abstract | To produce a sensitive and specific biosensor for Staphylococcus aureus, bacteriophages have been interfaced with a water-dispersible and environmentally stable metal-organic framework (MOF), NH2-MIL-53(Fe). The conjugation of the MOF with bacteriophages has been achieved through the use of glutaraldehyde as cross-linker. Highly sensitive detection of S. aureus in both synthetic and real samples was realized by the proposed MOF-bacteriophage' biosensor based on the photoluminescence quenching phenomena; limit of detection (31 CFU/mL) and range of detection (40 to 4 X 10(8) CFU/mL). This is the first report exploiting the use of an MOF-bacteriophage complex for the biosensing of S. aureus. The results of our study highlight that-the proposed biosensor is more sensitive than most of the previous methods while exhibiting some advanced features like specificity) regenerability, extended range of linear 'detection, and stability for long-term storage (even at room temperature). | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.title | MOF-Bacteriophage Biosensor for Highly Sensitive and Specific Detection of Staphylococcus aureus | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Ki-Hyun | - |
dc.identifier.doi | 10.1021/acsami.7b07818 | - |
dc.identifier.scopusid | 2-s2.0-85032804581 | - |
dc.identifier.wosid | 000412717600031 | - |
dc.identifier.bibliographicCitation | ACS APPLIED MATERIALS & INTERFACES, v.9, no.39, pp.33589 - 33598 | - |
dc.relation.isPartOf | ACS APPLIED MATERIALS & INTERFACES | - |
dc.citation.title | ACS APPLIED MATERIALS & INTERFACES | - |
dc.citation.volume | 9 | - |
dc.citation.number | 39 | - |
dc.citation.startPage | 33589 | - |
dc.citation.endPage | 33598 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.subject.keywordPlus | METAL-ORGANIC FRAMEWORKS | - |
dc.subject.keywordPlus | SCREEN-PRINTED IMMUNOSENSOR | - |
dc.subject.keywordPlus | PATHOGEN DETECTION | - |
dc.subject.keywordPlus | CARBON NANOTUBES | - |
dc.subject.keywordPlus | DRUG-DELIVERY | - |
dc.subject.keywordPlus | MAGNETIC NANOPARTICLES | - |
dc.subject.keywordPlus | FOODBORNE PATHOGENS | - |
dc.subject.keywordPlus | RAPID DETECTION | - |
dc.subject.keywordPlus | FOOD | - |
dc.subject.keywordPlus | ENVIRONMENT | - |
dc.subject.keywordAuthor | Staphylococcus aureus | - |
dc.subject.keywordAuthor | bacteriophages | - |
dc.subject.keywordAuthor | MOF | - |
dc.subject.keywordAuthor | fluorescence | - |
dc.subject.keywordAuthor | detection | - |
dc.identifier.url | https://pubs.acs.org/doi/10.1021/acsami.7b07818 | - |
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