Probe-based confocal laser endomicroscopy in the margin delineation of early gastric cancer for endoscopic submucosal dissection
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Jun Chul | - |
dc.contributor.author | Park, Yehyun | - |
dc.contributor.author | Kim, Hyun Ki | - |
dc.contributor.author | Jo, Jeong-Hyeon | - |
dc.contributor.author | Park, Chan Hyuk | - |
dc.contributor.author | Kim, Eun Hye | - |
dc.contributor.author | Jung, Da Hyun | - |
dc.contributor.author | Chung, Hyunsoo | - |
dc.contributor.author | Shin, Sung Kwan | - |
dc.contributor.author | Lee, Sang Kil | - |
dc.contributor.author | Lee, Yong Chan | - |
dc.date.accessioned | 2021-07-30T05:19:40Z | - |
dc.date.available | 2021-07-30T05:19:40Z | - |
dc.date.created | 2021-05-11 | - |
dc.date.issued | 2017-05 | - |
dc.identifier.issn | 0815-9319 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/4230 | - |
dc.description.abstract | Background and Aim We evaluated probe-based confocal laser endomicroscopy (pCLE) in the margin delineation of early gastric cancer (EGC) for endoscopic submucosal dissection in comparison with white-light imaging with chromoendoscopy (CE). Methods We conducted a prospective, randomized controlled study from November 2013 to October 2014 in a tertiary referral hospital. A total of 101 patients scheduled for endoscopic submucosal dissection due to differentiated EGC were randomized into pCLE and CE groups (pCLE 51, CE 50). Markings were made by electrocautery at the proximal and distal tumor margins, as determined by either pCLE or CE. The distance from the marking to the tumor margin was measured in the resected specimen histopathologically and was compared between the two groups by a linear mixed model. Results Among 104 lesions, 80 lesions with 149 markings (pCLE 68, CE 81) were analyzed after excluding undifferentiated EGCs (n = 8) and unidentifiable markings (n = 13). Although the complete resection rate showed no difference between the groups (94.6% vs 93.2%, P = 1.000), the median distance from the marking to the margin was shorter in the pCLE group (1.3 vs 1.8 mm, P = 0.525) and the proportion of the distance <1 mm was higher (43.9% vs 27.6%, P = 0.023) in the pCLE group. Finally, subgroup analysis with superficial flat lesions (18 lesions, 31 marking dots) showed a significantly decreased distance in the pCLE group (0.5 vs 3.1 mm, P = 0.007). Conclusions Among EGCs with superficial flat morphology, in which the accurate evaluation of lateral extent is difficult with CE, pCLE would be useful for more precise margin delineation. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.title | Probe-based confocal laser endomicroscopy in the margin delineation of early gastric cancer for endoscopic submucosal dissection | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Park, Chan Hyuk | - |
dc.identifier.doi | 10.1111/jgh.13635 | - |
dc.identifier.scopusid | 2-s2.0-85018700340 | - |
dc.identifier.wosid | 000400339400018 | - |
dc.identifier.bibliographicCitation | JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, v.32, no.5, pp.1046 - 1054 | - |
dc.relation.isPartOf | JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | - |
dc.citation.title | JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | - |
dc.citation.volume | 32 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 1046 | - |
dc.citation.endPage | 1054 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.subject.keywordPlus | MAGNIFYING ENDOSCOPY | - |
dc.subject.keywordPlus | IN-VIVO | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordPlus | BIOPSIES | - |
dc.subject.keywordPlus | EMR | - |
dc.subject.keywordAuthor | early gastric cancer | - |
dc.subject.keywordAuthor | endoscopic submucosal dissection | - |
dc.subject.keywordAuthor | probe-based confocal laser endomicroscopy | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1111/jgh.13635 | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
222, Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea+82-2-2220-1365
COPYRIGHT © 2021 HANYANG UNIVERSITY.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.