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Synthesis and biological evaluation of acylthiourea against DUSP1 inhibition
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Kim, Bo Yeon | - |
| dc.contributor.author | Yoon, Ji Hee | - |
| dc.contributor.author | Kim, Myeongbin | - |
| dc.contributor.author | Kim, Jae Nyoung | - |
| dc.contributor.author | Park, Hwangseo | - |
| dc.contributor.author | Ryu, Seong Eon | - |
| dc.contributor.author | Lee, Sangku | - |
| dc.date.accessioned | 2021-07-30T05:23:02Z | - |
| dc.date.available | 2021-07-30T05:23:02Z | - |
| dc.date.created | 2021-05-12 | - |
| dc.date.issued | 2019-07 | - |
| dc.identifier.issn | 0960-894X | - |
| dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/4550 | - |
| dc.description.abstract | Structure based virtual screening attempts to discover DUSP1 inhibitors have yielded a scaffold featuring benzoxazole and acylthiourea pharmacophore. A series of its analogues were synthesized to explore structure activity relationship (SAR) of DUSP1 inhibition. | - |
| dc.language | 영어 | - |
| dc.language.iso | en | - |
| dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | - |
| dc.title | Synthesis and biological evaluation of acylthiourea against DUSP1 inhibition | - |
| dc.type | Article | - |
| dc.contributor.affiliatedAuthor | Ryu, Seong Eon | - |
| dc.identifier.doi | 10.1016/j.bmcl.2019.05.021 | - |
| dc.identifier.scopusid | 2-s2.0-85065625831 | - |
| dc.identifier.wosid | 000469785600011 | - |
| dc.identifier.bibliographicCitation | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.29, no.14, pp.1746 - 1748 | - |
| dc.relation.isPartOf | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - |
| dc.citation.title | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - |
| dc.citation.volume | 29 | - |
| dc.citation.number | 14 | - |
| dc.citation.startPage | 1746 | - |
| dc.citation.endPage | 1748 | - |
| dc.type.rims | ART | - |
| dc.type.docType | Article | - |
| dc.description.journalClass | 1 | - |
| dc.description.isOpenAccess | N | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
| dc.relation.journalResearchArea | Chemistry | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
| dc.subject.keywordPlus | DUAL-SPECIFICITY PHOSPHATASE | - |
| dc.subject.keywordPlus | NEGATIVE REGULATOR | - |
| dc.subject.keywordPlus | KINASES | - |
| dc.subject.keywordPlus | VHR | - |
| dc.subject.keywordPlus | ERK | - |
| dc.subject.keywordAuthor | Dual specificity phosphatase | - |
| dc.subject.keywordAuthor | Mitogen-activated protein kinase | - |
| dc.subject.keywordAuthor | Enzyme inhibition | - |
| dc.subject.keywordAuthor | Structure activity relationship | - |
| dc.subject.keywordAuthor | Cancer | - |
| dc.identifier.url | https://linkinghub.elsevier.com/retrieve/pii/S0960894X1930318X | - |
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Related Researcher
- Ryu, Seong Eon
- COLLEGE OF ENGINEERING (DEPARTMENT OF BIOENGINEERING)