Vitamin D receptor FokI, BsmI, and TaqI polymorphisms and susceptibility to rheumatoid arthritis A meta-analysis
DC Field | Value | Language |
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dc.contributor.author | Song, G. G. | - |
dc.contributor.author | Bae, Sang Cheol | - |
dc.contributor.author | Lee, Y. H. | - |
dc.date.accessioned | 2021-07-30T05:28:29Z | - |
dc.date.available | 2021-07-30T05:28:29Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2016-04 | - |
dc.identifier.issn | 0340-1855 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/5069 | - |
dc.description.abstract | Objective The aim of this study was to explore whether vitamin D receptor (VDR) polymorphisms are associated with susceptibility to rheumatoid arthritis (RA). Methods Meta-analyses were conducted on the associations between the VDR FokI, BsmI, and TaqI polymorphisms and RA. Results A total of seven studies were considered in the meta-analysis, involving a total of 923 patients and 912 controls. Meta-analysis of the VDR FokI polymorphism showed no association between RA and the F allele in the entire studied cohort (odds ratio, OR = 1.1740, 95 % confidence interval, CI = 0.994–1.387, p = 0.059). However, stratification by ethnicity revealed a significant association between the F allele and RA in Europeans (OR = 1.402, 95 % CI = 1.126–1.746, p = 0.003). Furthermore, an association was found between RA and the VDR FokI polymorphism using both the dominant model and homozygote contrast. Meta-analysis revealed no association between RA and the VDR BsmI B and TaqI T polymorphisms in Europeans (OR for the B allele = 1.065, 95 % CI = 0.911–1.245, p = 0.427; OR for the T allele = 1.065, 95 % CI = 0.834–1.361, p = 0.613). Conclusion This meta-analysis suggests that the VDR FokI polymorphism is associated with susceptibility to RA in European populations. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | SPRINGER HEIDELBERG | - |
dc.title | Vitamin D receptor FokI, BsmI, and TaqI polymorphisms and susceptibility to rheumatoid arthritis A meta-analysis | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Bae, Sang Cheol | - |
dc.identifier.doi | 10.1007/s00393-015-1581-6 | - |
dc.identifier.scopusid | 2-s2.0-84941336537 | - |
dc.identifier.wosid | 000373646700014 | - |
dc.identifier.bibliographicCitation | ZEITSCHRIFT FUR RHEUMATOLOGIE, v.75, no.3, pp.322 - 329 | - |
dc.relation.isPartOf | ZEITSCHRIFT FUR RHEUMATOLOGIE | - |
dc.citation.title | ZEITSCHRIFT FUR RHEUMATOLOGIE | - |
dc.citation.volume | 75 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 322 | - |
dc.citation.endPage | 329 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Rheumatology | - |
dc.relation.journalWebOfScienceCategory | Rheumatology | - |
dc.subject.keywordPlus | SYSTEMIC-LUPUS-ERYTHEMATOSUS | - |
dc.subject.keywordPlus | GENE POLYMORPHISMS | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | OSTEOPOROSIS | - |
dc.subject.keywordPlus | POPULATION | - |
dc.subject.keywordPlus | GENOTYPES | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordAuthor | Immune system | - |
dc.subject.keywordAuthor | Autoimmune diseases | - |
dc.subject.keywordAuthor | Hormone receptors, nuclear | - |
dc.subject.keywordAuthor | MEDLINE | - |
dc.subject.keywordAuthor | Linkage disequilibrium | - |
dc.identifier.url | https://link.springer.com/article/10.1007/s00393-015-1581-6 | - |
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