Oxaliplatin-induced sinusoidal obstruction syndrome mimicking metastatic colon cancer in the liver
DC Field | Value | Language |
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dc.contributor.author | Choi, Jung-Hye | - |
dc.contributor.author | Won, Young-Woong | - |
dc.contributor.author | Kim, Hyun Sung | - |
dc.contributor.author | Oh, Young-Ha | - |
dc.contributor.author | Lim, Sanghyeok | - |
dc.contributor.author | Kim, Han-Joon | - |
dc.date.accessioned | 2021-07-30T05:35:45Z | - |
dc.date.available | 2021-07-30T05:35:45Z | - |
dc.date.created | 2021-05-11 | - |
dc.date.issued | 2016-04 | - |
dc.identifier.issn | 1792-1074 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/5629 | - |
dc.description.abstract | Oxaliplatin is an effective chemotherapeutic agent for the treatment of colorectal cancer; however, it may cause liver injury, particularly sinusoidal obstruction syndrome (SOS). Although SOS does not usually present with focal lesions on radiological images, the present study describes the case of a 22-year-old woman with oxaliplatin-induced SOS mimicking metastatic colon cancer in the liver. An abdominal computed tomography revealed a novel 1 cm, low-density lesion in segment 1 of the liver following the administration of the fourth round of oxaliplatin-based adjuvant chemotherapy for stage III colon cancer. Since the lesion was indistinguishable from metastasis, even with detailed imaging studies, including magnetic resonance imaging and positron emission tomography-computed tomography, an isolated caudate lobectomy was planned. The cut surface of the resected liver showed a localized reddish congested lesion measuring 1.4 cm in diameter. The adjacent hepatic parenchyma also demonstrated diffuse sinusoidal congestion with a nutmeg-like appearance. Histologically, the lesion exhibited severe sinusoidal congestion with peliosis hepatis-like features. The widened sinusoidal space was outlined by markedly attenuated hepatic cords and filled with erythrocytes. The final diagnosis was oxaliplatin-induced SOS. The patient recovered completely and was relapse-free at the time of writing. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | SPANDIDOS PUBL LTD | - |
dc.title | Oxaliplatin-induced sinusoidal obstruction syndrome mimicking metastatic colon cancer in the liver | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Choi, Jung-Hye | - |
dc.contributor.affiliatedAuthor | Won, Young-Woong | - |
dc.contributor.affiliatedAuthor | Oh, Young-Ha | - |
dc.identifier.doi | 10.3892/ol.2016.4286 | - |
dc.identifier.scopusid | 2-s2.0-84960461916 | - |
dc.identifier.wosid | 000373478900089 | - |
dc.identifier.bibliographicCitation | ONCOLOGY LETTERS, v.11, no.4, pp.2861 - 2864 | - |
dc.relation.isPartOf | ONCOLOGY LETTERS | - |
dc.citation.title | ONCOLOGY LETTERS | - |
dc.citation.volume | 11 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 2861 | - |
dc.citation.endPage | 2864 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.subject.keywordPlus | COLORECTAL-CANCER | - |
dc.subject.keywordPlus | CHEMOTHERAPY | - |
dc.subject.keywordPlus | FLUOROURACIL | - |
dc.subject.keywordPlus | INJURY | - |
dc.subject.keywordAuthor | oxaliplatin | - |
dc.subject.keywordAuthor | sinusoidal obstruction syndrome | - |
dc.subject.keywordAuthor | colon cancer | - |
dc.identifier.url | https://www.spandidos-publications.com/10.3892/ol.2016.4286 | - |
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