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Synthetic Approach toward Novel Strained Macrolide, Pondaplin : Application of IMDA Reaction as Macrocyclization Strategy
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | 조천규 | - |
| dc.date.accessioned | 2021-08-04T03:54:00Z | - |
| dc.date.available | 2021-08-04T03:54:00Z | - |
| dc.date.issued | 2005-10-22 | - |
| dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/71435 | - |
| dc.description.abstract | Podalin, isolated in 1999 from the leaves of Annona graba shows potent cytotoxicity against breast and prostate cancer cells. Strained ansa-chain presents a significant challenge for the total synthesis of this (9)-paracyclophane natural product. Our approach toward this molecule is based on the IMDA(intramolecular Diels-Alder) reaction and subsequent aromatization for the formation of macrolide. Preliminary investigation of Stille-transetherification-IMDA sequences is presented | - |
| dc.title | Synthetic Approach toward Novel Strained Macrolide, Pondaplin : Application of IMDA Reaction as Macrocyclization Strategy | - |
| dc.type | Conference | - |
| dc.citation.conferenceName | 제 96회 대한화학회 | - |
| dc.citation.conferencePlace | 연세대학교(원주) | - |
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Related Researcher
- Cho, Cheon Gyu
- COLLEGE OF NATURAL SCIENCES (DEPARTMENT OF CHEMISTRY)