Comparison of clinical characteristics of ALS subgroups, rapid progressive group vs. steady progressive group - Preliminary study on ALS natural history.

Abstract

Amyotrophic lateral sclerosis (ALS) is a relentlessly devastating disease affecting selectively motor nuerons of central nervous system in which motoneurons die over a relatively short time period. Despite the accurate diagnostic criteria of ALS, disease progression and prognosis if somewhat different from each patients. We conducted this study to preliminary evaluate the factors affecting prognosis of ALS patients.