Lipid indices as simple and clinically useful surrogate markers for insulin resistance in the U.S. population
DC Field | Value | Language |
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dc.contributor.author | Lee, Juncheol | - |
dc.contributor.author | Kim, Bongyoung | - |
dc.contributor.author | Kim, Wonhee | - |
dc.contributor.author | Ahn, Chiwon | - |
dc.contributor.author | Choi, Hyun Young | - |
dc.contributor.author | Kim, Jae Guk | - |
dc.contributor.author | Kim, Jihoon | - |
dc.contributor.author | Shin Hyungoo | - |
dc.contributor.author | Kang, Jun Goo | - |
dc.contributor.author | Moon, Shinje | - |
dc.date.accessioned | 2021-08-02T08:25:53Z | - |
dc.date.available | 2021-08-02T08:25:53Z | - |
dc.date.created | 2021-05-13 | - |
dc.date.issued | 2021-12 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/7940 | - |
dc.description.abstract | This study aimed to compare the accuracy of novel lipid indices, including the visceral adiposity index (VAI), lipid accumulation product (LAP), triglycerides and glucose (TyG) index, TyG-body mass index (TyG-BMI), and TyG-waist circumference (TyG-WC), in identifying insulin resistance and establish valid cutoff values. This cross-sectional study used the data of 11,378 adults, derived from the United States National Health and Nutrition Examination Survey (1999?2016). Insulin resistance was defined as a homeostasis model assessment-insulin resistance value above the 75th percentile for each sex and race/ethnicities. The area under the curves (AUCs) were as follows: VAI, 0.735; LAP, 0.796; TyG index, 0.723; TyG-BMI, 0.823, and; TyG-WC, 0.822. The AUCs for TyG-BMI and TyG-WC were significantly higher than those for VAI, LAP, and TyG index (vs. TyG-BMI, p < 0.001; vs. TyG-WC, p < 0.001). The cutoff values were as follows: VAI: men 1.65, women 1.65; LAP: men 42.5, women 42.5; TyG index: men 4.665, women 4.575; TyG-BMI: men 135.5, women 135.5; and TyG-WC: men 461.5, women 440.5. Given that lipid indices can be easily calculated with routine laboratory tests, these values may be useful markers for insulin resistance risk assessments in clinical settings. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Nature Research | - |
dc.title | Lipid indices as simple and clinically useful surrogate markers for insulin resistance in the U.S. population | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Bongyoung | - |
dc.contributor.affiliatedAuthor | Shin Hyungoo | - |
dc.identifier.doi | 10.1038/s41598-021-82053-2 | - |
dc.identifier.scopusid | 2-s2.0-85099873041 | - |
dc.identifier.wosid | 000668347900004 | - |
dc.identifier.bibliographicCitation | Scientific Reports, v.11, no.1, pp.1 - 9 | - |
dc.relation.isPartOf | Scientific Reports | - |
dc.citation.title | Scientific Reports | - |
dc.citation.volume | 11 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 9 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordPlus | VISCERAL ADIPOSITY INDEX | - |
dc.subject.keywordPlus | FATTY-ACIDS | - |
dc.subject.keywordPlus | ACCUMULATION PRODUCT | - |
dc.subject.keywordPlus | GLUCOSE | - |
dc.subject.keywordPlus | MUSCLE | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | TISSUE | - |
dc.subject.keywordPlus | WOMEN | - |
dc.subject.keywordPlus | HYPERINSULINEMIA | - |
dc.subject.keywordPlus | DIACYLGLYCEROL | - |
dc.identifier.url | https://www.nature.com/articles/s41598-021-82053-2 | - |
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