Association between Antibiotic Consumption and Incidence of Clostridioides difficile Infection in a Hospital
DC Field | Value | Language |
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dc.contributor.author | Kim, Bongyoung | - |
dc.contributor.author | Kim, Jieun | - |
dc.contributor.author | Pai, Hyunjoo | - |
dc.date.accessioned | 2021-08-02T08:28:43Z | - |
dc.date.available | 2021-08-02T08:28:43Z | - |
dc.date.created | 2021-05-11 | - |
dc.date.issued | 2020-12 | - |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/8180 | - |
dc.description.abstract | Previous exposure to antimicrobials is a major risk factor for Clostridioides difficile infection (CDI). Antibiotic prescription and C. difficile toxin assay records of patients admitted to a tertiary hospital in Korea from 2009 to 2013 were collected to investigate the association between antibiotic consumption and CDI incidence. A Spearman's correlation analysis between CDI incidence (positive result of toxin assay/10,000 admissions) and antibiotic consumption (defined daily dose/1,000 patient-days) was performed on a monthly basis. Using the matched month approach, we found a significant correlation between CDI rate and moxifloxacin consumption (Spearman's r = 0.351, P < 0.001). Furthermore, using the onemonth delay approach, we found that the consumption of clindamycin (Spearman's r = 0.272, P = 0.037) and moxifloxacin (Spearman's r = 0.297, P = 0.022) was significantly correlated with CDI incidence. Extended-spectrum cephalosporins did not have any effect on CDI incidence. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN ACAD MEDICAL SCIENCES | - |
dc.title | Association between Antibiotic Consumption and Incidence of Clostridioides difficile Infection in a Hospital | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Bongyoung | - |
dc.contributor.affiliatedAuthor | Kim, Jieun | - |
dc.identifier.doi | 10.3346/jkms.2020.35.e407 | - |
dc.identifier.scopusid | 2-s2.0-85097484294 | - |
dc.identifier.wosid | 000600132100005 | - |
dc.identifier.bibliographicCitation | JOURNAL OF KOREAN MEDICAL SCIENCE, v.35, no.47, pp.1 - 6 | - |
dc.relation.isPartOf | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.citation.title | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.citation.volume | 35 | - |
dc.citation.number | 47 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 6 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002654585 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | EPIDEMIOLOGY | - |
dc.subject.keywordPlus | DIARRHEA | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | EXPOSURE | - |
dc.subject.keywordAuthor | Clostridioides difficile | - |
dc.subject.keywordAuthor | Antibiotics | - |
dc.subject.keywordAuthor | Correlation | - |
dc.subject.keywordAuthor | Stewardship | - |
dc.subject.keywordAuthor | Korea | - |
dc.identifier.url | https://jkms.org/DOIx.php?id=10.3346/jkms.2020.35.e407 | - |
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