Association between insulin resistance and risk of atrial fibrillation in non-diabetics
DC Field | Value | Language |
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dc.contributor.author | Lee, Yonggu | - |
dc.contributor.author | Cha, Sung Joo | - |
dc.contributor.author | Park, Jung-Hwan | - |
dc.contributor.author | Shin, Jeong-Hun | - |
dc.contributor.author | Lim, Young-Hyo | - |
dc.contributor.author | Park, Hwan-Cheol | - |
dc.contributor.author | Shin, Jinho | - |
dc.contributor.author | Kim, Chun Ki | - |
dc.contributor.author | Park, Jin-Kyu | - |
dc.date.accessioned | 2021-08-02T08:28:43Z | - |
dc.date.available | 2021-08-02T08:28:43Z | - |
dc.date.created | 2021-05-11 | - |
dc.date.issued | 2020-12 | - |
dc.identifier.issn | 2047-4873 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/8181 | - |
dc.description.abstract | Aims Previous studies from Western countries have been unable to demonstrate a relationship between insulin resistance and new-onset atrial fibrillation. We aimed to evaluate this relationship in the nondiabetic Asian population. Methods Between 2001-2003, 8175 adults (mean age 51.5 years, 53% women) without both existing atrial fibrillation and diabetes and with insulin resistance measures at baseline were enrolled and were followed by biennial electrocardiograms thereafter until 2014. We constructed multivariable-adjusted Cox proportional hazard models for risk of incident atrial fibrillation. Results Over a median follow-up of 12.3 years, 136 participants (1.89/1000 person-years) developed atrial fibrillation. Higher homeostasis model assessment of insulin resistance (HOMA-IR) was independently associated with newly developed atrial fibrillation (hazard ratio 1.61, 95% confidence interval 1.14-2.28). Atrial fibrillation development increased at the HOMA-IR levels approximately between 1-2.5, and then plateaued afterwards (p = 0.031). Conclusion There is a significant relationship between insulin resistance and atrial fibrillation development independent of other known risk factors, including obesity in a nondiabetic Asian population. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | SAGE PUBLICATIONS LTD | - |
dc.title | Association between insulin resistance and risk of atrial fibrillation in non-diabetics | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Yonggu | - |
dc.contributor.affiliatedAuthor | Park, Jung-Hwan | - |
dc.contributor.affiliatedAuthor | Shin, Jeong-Hun | - |
dc.contributor.affiliatedAuthor | Lim, Young-Hyo | - |
dc.contributor.affiliatedAuthor | Park, Hwan-Cheol | - |
dc.contributor.affiliatedAuthor | Shin, Jinho | - |
dc.contributor.affiliatedAuthor | Park, Jin-Kyu | - |
dc.identifier.doi | 10.1177/2047487320908706 | - |
dc.identifier.scopusid | 2-s2.0-85081652594 | - |
dc.identifier.wosid | 000517707600001 | - |
dc.identifier.bibliographicCitation | EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY, v.27, no.18, pp.1934 - 1941 | - |
dc.relation.isPartOf | EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY | - |
dc.citation.title | EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY | - |
dc.citation.volume | 27 | - |
dc.citation.number | 18 | - |
dc.citation.startPage | 1934 | - |
dc.citation.endPage | 1941 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.subject.keywordPlus | EPIDEMIOLOGY | - |
dc.subject.keywordPlus | PATHOPHYSIOLOGY | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | MECHANISMS | - |
dc.subject.keywordPlus | SECRETION | - |
dc.subject.keywordPlus | MELLITUS | - |
dc.subject.keywordPlus | OBESITY | - |
dc.subject.keywordAuthor | Insulin resistance | - |
dc.subject.keywordAuthor | atrial fibrillation | - |
dc.subject.keywordAuthor | obesity | - |
dc.subject.keywordAuthor | epidemiology | - |
dc.identifier.url | https://academic.oup.com/eurjpc/article/27/18/1934/6125511 | - |
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