Impact of the timing of Helicobacter pylori eradication on the risk of development of metachronous lesions after treatment of early gastric cancer: a population-based cohort study
DC Field | Value | Language |
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dc.contributor.author | Kim, Hyun Ju | - |
dc.contributor.author | Kim, Yun Jin | - |
dc.contributor.author | Seo, Seung In | - |
dc.contributor.author | Shin, Woon Geon | - |
dc.contributor.author | Park, Chan Hyuk | - |
dc.date.accessioned | 2021-08-02T08:52:56Z | - |
dc.date.available | 2021-08-02T08:52:56Z | - |
dc.date.created | 2021-05-11 | - |
dc.date.issued | 2020-09 | - |
dc.identifier.issn | 0016-5107 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/8987 | - |
dc.description.abstract | Background and Aims: Helicobacter pylori eradication can reduce the risk of metachronous lesions after the treatment of early gastric cancer. We aimed to analyze the impact of the timing of H pylori eradication on metachronous recurrence. Methods: Data of patients who underwent endoscopic resection or partial gastrectomy for early stage gastric cancer and received H pylori eradication therapy were obtained from the Korean National Health Insurance Service database. Patients were classified into 3 groups according to the timing of the prescription for H pylori eradication: preresection; within 1 year postresection; and >1 year postresection. Results: Among 19,767 patients, 7452 and 12,315 underwent endoscopic resection and surgery, respectively. The 5-year cumulative incidence of metachronous lesions after endoscopic resection was 14.0% in the preresection group, 12.3% in the within 1 year postresection group, and 16.9% in the >1 year postresection group. Surgery was performed in 1.2% of the preresection group, 1.3% of the within 1 year postresection group, and 2.9% of the >1 year postresection group. The within 1 year postresection group had a lower risk of development of metachronous lesions than the >1 year postresection group (hazard ratio [95% confidence interval]: after endoscopic resection, 0.79 [0.65-0.95]; after surgery, 0.39 [0.28-0.53]). The risk of development of metachronous lesions did not differ between the preresection and within 1 year postresection groups. Conclusion: Prescription of H pylori eradication therapy within 1 year after gastric cancer treatment reduces the risk of development of metachronous gastric neoplasms compared with a late prescription of eradication therapy in patients undergoing endoscopic resection and those undergoing surgery. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | MOSBY-ELSEVIER | - |
dc.title | Impact of the timing of Helicobacter pylori eradication on the risk of development of metachronous lesions after treatment of early gastric cancer: a population-based cohort study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Park, Chan Hyuk | - |
dc.identifier.doi | 10.1016/j.gie.2020.05.029 | - |
dc.identifier.scopusid | 2-s2.0-85089512977 | - |
dc.identifier.wosid | 000565275500021 | - |
dc.identifier.bibliographicCitation | GASTROINTESTINAL ENDOSCOPY, v.92, no.3, pp.613 - 622.e1 | - |
dc.relation.isPartOf | GASTROINTESTINAL ENDOSCOPY | - |
dc.citation.title | GASTROINTESTINAL ENDOSCOPY | - |
dc.citation.volume | 92 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 613 | - |
dc.citation.endPage | 622.e1 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.subject.keywordPlus | ENDOSCOPIC RESECTION | - |
dc.subject.keywordPlus | DISTAL GASTRECTOMY | - |
dc.subject.keywordPlus | REMNANT STOMACH | - |
dc.subject.keywordPlus | CARCINOMA | - |
dc.subject.keywordPlus | TRIAL | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0016510720343649?via%3Dihub | - |
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