Risk factors for postoperative recurrence in Korean patients with Crohn’s disease
DC Field | Value | Language |
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dc.contributor.author | Kim, Sung Bae | - |
dc.contributor.author | Cheon, Jae Hee | - |
dc.contributor.author | Park, Jae Jun | - |
dc.contributor.author | Kim, Eun Soo | - |
dc.contributor.author | Jeon, Seong Woo | - |
dc.contributor.author | Jung, Sung-Ae | - |
dc.contributor.author | Park, Dong Il | - |
dc.contributor.author | Lee, Chang Kyun | - |
dc.contributor.author | Im, Jong Pil | - |
dc.contributor.author | Kim, You Sun | - |
dc.contributor.author | Kim, Hyun Soo | - |
dc.contributor.author | Lee, Jun | - |
dc.contributor.author | Eun, Chang Soo | - |
dc.contributor.author | Lee, Jeong Mi | - |
dc.contributor.author | Jang, Byung Ik | - |
dc.contributor.author | Seo, Geom Seog | - |
dc.date.accessioned | 2021-08-02T09:27:39Z | - |
dc.date.available | 2021-08-02T09:27:39Z | - |
dc.date.created | 2021-05-13 | - |
dc.date.issued | 2020-05 | - |
dc.identifier.issn | 1976-2283 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/9814 | - |
dc.description.abstract | Background/Aims: A considerable number of patients with Crohn’s disease still need intestinal resection surgery. Postoperative recurrence is an important issue in Crohn’s disease management, including the selection of high-risk patients. Eastern Asian patients showed several differences from Caucasian patients. Therefore, we investigated the postoperative surgical recurrence outcome and identified risk factors in Korean patients. Methods: Clinical data of 372 patients with Crohn’s disease who underwent first intestinal resection between January 2004 and August 2014 at 14 hospitals in Korea were retrospectively reviewed. Results: Over the follow-up period, 50 patients (17.1%) showed surgical recurrence. The cumulative surgical recurrence rate was 6.5% at 1 year and 15.4% at 7 years. Age under 16 (p=0.011; hazard ratio [HR], 5.136; 95% confidence interval [CI], 1.576 to 16.731), colonic involvement (p=0.023; HR, 2.011; 95% CI, 1.102 to 3.670), and the presence of perianal disease at surgery (p=0.008; HR, 2.239; 95% CI, 1.236 to 4.059) were independent risk factors associated with surgical recurrence. Postoperative thiopurine treatment (p=0.002; HR, 0.393; 95% CI, 0.218 to 0.710) was a protective factor for surgical recurrence. Conclusions: Among the disease characteristics at surgery, younger age, colonic location, and perianal lesions were independent risk factors for surgical recurrence. Postoperative thiopurine treatment significantly reduced the incidence of surgical recurrence. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | EDITORIAL OFFICE GUT & LIVER | - |
dc.title | Risk factors for postoperative recurrence in Korean patients with Crohn’s disease | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Eun, Chang Soo | - |
dc.identifier.doi | 10.5009/gnl19085 | - |
dc.identifier.scopusid | 2-s2.0-85084694307 | - |
dc.identifier.wosid | 000533543100010 | - |
dc.identifier.bibliographicCitation | GUT AND LIVER, v.14, no.3, pp.331 - 337 | - |
dc.relation.isPartOf | GUT AND LIVER | - |
dc.citation.title | GUT AND LIVER | - |
dc.citation.volume | 14 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 331 | - |
dc.citation.endPage | 337 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002586718 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.subject.keywordPlus | INFLAMMATORY-BOWEL-DISEASE | - |
dc.subject.keywordPlus | CLINICAL CHARACTERISTICS | - |
dc.subject.keywordPlus | ILEOCOLIC RESECTION | - |
dc.subject.keywordPlus | SURGICAL RECURRENCE | - |
dc.subject.keywordPlus | NATURAL-HISTORY | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | WESTERN | - |
dc.subject.keywordPlus | OUTCOMES | - |
dc.subject.keywordPlus | EASTERN | - |
dc.subject.keywordAuthor | Crohn disease | - |
dc.subject.keywordAuthor | Recurrence | - |
dc.subject.keywordAuthor | Risk factors | - |
dc.subject.keywordAuthor | Surgery | - |
dc.subject.keywordAuthor | Thiopurine | - |
dc.identifier.url | https://www.gutnliver.org/journal/view.html?doi=10.5009/gnl19085 | - |
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