Ten-year trends in antibiotic usage at a tertiary care hospital in Korea, 2004 to 2013
DC Field | Value | Language |
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dc.contributor.author | Kim, Bongyoung | - |
dc.contributor.author | Hwang, Hyeonjun | - |
dc.contributor.author | Kim, Jieun | - |
dc.contributor.author | Lee, Myoung-jae | - |
dc.contributor.author | Pai, Hyunjoo | - |
dc.date.accessioned | 2021-08-02T09:28:17Z | - |
dc.date.available | 2021-08-02T09:28:17Z | - |
dc.date.created | 2021-05-11 | - |
dc.date.issued | 2020-05 | - |
dc.identifier.issn | 1226-3303 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/9867 | - |
dc.description.abstract | Background/Aims: This study was performed to evaluate trends in antibiotic usage at a tertiary care hospital in Korea. Methods: This study collated antibiotic prescription data and total patient days for inpatients at a tertiary care hospital in Korea between 2004 and 2013. The consumption of each class of antibiotic was converted to defined daily dose (DDD)/1.,000 patient-days. We defined 3rd generation cephalosporins, 4th generation cephalosporins, beta-lactam/beta-lactamase inhibitors, and fluoroquinolones as broad-spectrum antibiotics; carbapenems, tigecycline, glycopeptides, oxazolidinone, and polymyxin were defined as antibiotics against multidrug-resistant (MDR) pathogens. Other antibiotic classes were defined as nonbroad-spectrum antibiotics. Results: Mean antibiotic consumption was 920.69 DDD/1,000 patient-days. The proportions of broad-spectrum antibiotics, antibiotics against MDR pathogens, and nonbroad-spectrum antibiotics were 41.8% (384.48/920.69), 3.5% (32.24/920.69), and 54.7% (503.97/920.69), respectively. Consumption of broad-spectrum antibiotics (coefficient for time 0.141; p = 0.049) and antibiotics against MDR pathogens (coefficient for time 0.185; p < 0.001) showed a significant increasing trend over the study period. Nonbroad-spectrum antibiotic consumption showed a significant decreasing trend over the study period (coefficient for time -2.601; p < 0.001). Conclusions: Over the 10-year period, a stepwise increase in the consumption of broad-spectrum antibiotics and antibiotics against MDR pathogens was observed at a tertiary care hospital in Korea. Conversely, during the same period, nonbroad-spectrum antibiotic consumption showed a significant decreasing trend. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN ASSOC INTERNAL MEDICINE | - |
dc.title | Ten-year trends in antibiotic usage at a tertiary care hospital in Korea, 2004 to 2013 | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Bongyoung | - |
dc.contributor.affiliatedAuthor | Kim, Jieun | - |
dc.contributor.affiliatedAuthor | Pai, Hyunjoo | - |
dc.identifier.doi | 10.3904/kjim.2017.332 | - |
dc.identifier.scopusid | 2-s2.0-85084528116 | - |
dc.identifier.wosid | 000530244800022 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF INTERNAL MEDICINE, v.35, no.3, pp.703 - 713 | - |
dc.relation.isPartOf | KOREAN JOURNAL OF INTERNAL MEDICINE | - |
dc.citation.title | KOREAN JOURNAL OF INTERNAL MEDICINE | - |
dc.citation.volume | 35 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 703 | - |
dc.citation.endPage | 713 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002580417 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | INFECTIOUS-DISEASES-SOCIETY | - |
dc.subject.keywordPlus | COMMUNITY-ACQUIRED PNEUMONIA | - |
dc.subject.keywordPlus | GRAM-NEGATIVE BACILLI | - |
dc.subject.keywordPlus | ANTIMICROBIAL SUSCEPTIBILITY | - |
dc.subject.keywordPlus | EPIDEMIOLOGY | - |
dc.subject.keywordPlus | GUIDELINES | - |
dc.subject.keywordPlus | RESISTANCE | - |
dc.subject.keywordPlus | EMERGENCE | - |
dc.subject.keywordPlus | AMERICA | - |
dc.subject.keywordPlus | PROGRAM | - |
dc.subject.keywordAuthor | Anti-bacterial agents | - |
dc.subject.keywordAuthor | Hospitals | - |
dc.subject.keywordAuthor | Korea | - |
dc.identifier.url | https://www.kjim.org/journal/view.php?doi=10.3904/kjim.2017.332 | - |
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