Heparin-immobilized pluronic/PVA composite microparticles for the sustained delivery of ionic drug
DC Field | Value | Language |
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dc.contributor.author | Park, Hwa Young | - |
dc.contributor.author | Oh, Keun Sang | - |
dc.contributor.author | Koo, Hyoung Mo | - |
dc.contributor.author | Cho, Sun Hang | - |
dc.contributor.author | Chung, Sang Jun | - |
dc.contributor.author | Lim, Yong Taik | - |
dc.contributor.author | Kim, Dongmin | - |
dc.contributor.author | Yuk, Soon Hong | - |
dc.date.accessioned | 2022-01-13T06:44:06Z | - |
dc.date.available | 2022-01-13T06:44:06Z | - |
dc.date.created | 2022-01-04 | - |
dc.date.issued | 2008-03 | - |
dc.identifier.issn | 0265-2048 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hongik/handle/2020.sw.hongik/22770 | - |
dc.description.abstract | Heparin-immobilized Pluronic (F-68)/Polyvinylalcohol (PVA) composite microparticles were designed and characterized for the sustained drug delivery of ionic drug. Venlafaxine, antidepressant medication, was used as a model drug. For the efficient loading of ionic drug, heparin was immobilized into F-68/PVA composite microparticles. Differential scanning calorimetry (DSC) was used to understand the intra/intermolecular interactions in the heparin-immobilized F-68/PVA composite gels containing model drug. For the application as a sustained drug delivery system, the loading amount and release pattern of loaded drug were measured using high performance liquid chromatography (HPLC). | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | TAYLOR & FRANCIS LTD | - |
dc.subject | EXCHANGE RESINS | - |
dc.subject | RELEASE | - |
dc.subject | SYSTEM | - |
dc.subject | NANOPARTICLES | - |
dc.subject | MICROSPHERES | - |
dc.title | Heparin-immobilized pluronic/PVA composite microparticles for the sustained delivery of ionic drug | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Dongmin | - |
dc.identifier.doi | 10.1080/02652040701800917 | - |
dc.identifier.scopusid | 2-s2.0-39049167360 | - |
dc.identifier.wosid | 000253946400004 | - |
dc.identifier.bibliographicCitation | JOURNAL OF MICROENCAPSULATION, v.25, no.2, pp.106 - 110 | - |
dc.relation.isPartOf | JOURNAL OF MICROENCAPSULATION | - |
dc.citation.title | JOURNAL OF MICROENCAPSULATION | - |
dc.citation.volume | 25 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 106 | - |
dc.citation.endPage | 110 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Applied | - |
dc.relation.journalWebOfScienceCategory | Engineering, Chemical | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.subject.keywordPlus | EXCHANGE RESINS | - |
dc.subject.keywordPlus | RELEASE | - |
dc.subject.keywordPlus | SYSTEM | - |
dc.subject.keywordPlus | NANOPARTICLES | - |
dc.subject.keywordPlus | MICROSPHERES | - |
dc.subject.keywordAuthor | microparticle | - |
dc.subject.keywordAuthor | pluronic | - |
dc.subject.keywordAuthor | polyvinylalcohol | - |
dc.subject.keywordAuthor | heparin | - |
dc.subject.keywordAuthor | sustained release of ionic drug | - |
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